UJI INVIVO AKTIVITAS DIURETIKA EKSTRAK ETANOL 70% DAUN UNGU (Graptophyllum pictum (L) Griff) PADA MENCIT PUTIH JANTAN GALUR WISTAR

Authors

  • Recta Olivia Umboro Universitas Qamarul Huda Badaruddin
  • Dedent Eka Bimmaharyanto Universitas Qamarul Huda Badaruddin
  • Fitri Apriliany Universitas Bumigora
  • Iva Rinia Dewi Sekolah Tinggi Ilmu Kesehatan Ibnu Sina Ajibarang

DOI:

https://doi.org/10.36387/jifi.v5i2.1137

Keywords:

Invivo, Ekstract, Graptophyllum pictum (L) Griff,, Diuretica

Abstract

Traditionally, daun ungu plant (Graptophyllum pictum (L) Griff) has been known

to have pharmacological effects that can help with a variety of health issues. This

plant’s flavonoid compounds content is thought to have diuretic activity in this

plant is believed to have activity. The purpose of this study is to determine the

diuretic activity and optimal dose of etanol extract of 70% daun ungu administered

orally to male white mice. This is an experimental study with a completely

randomized design (CRD) that includes 1 negative control group (Na.CMC 0.5%),

1 positive control group (furosemide 40 mg) and 3 test groups of 70% daun ungu

ethanol extract doses of 10 mg/kg BW, 25 mg/kg BW and 40 mg/kg BW with urine

volume test parameters. One-way ANOVA and Kruskal-Wallis statistical test were

used to analyze the data. The results showed that one-way ANOVA revealed a P <

0.05 (0.012), and P ≤ 0.05 (0.051) for the Kruskal-Wallis test. It can be concluded

that 70% daun ungu etahanol exctract has effective diuretics, with an optimal dose

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Published

2022-12-31

How to Cite

1.
Umboro RO, Bimmaharyanto DE, Apriliany F, Dewi IR. UJI INVIVO AKTIVITAS DIURETIKA EKSTRAK ETANOL 70% DAUN UNGU (Graptophyllum pictum (L) Griff) PADA MENCIT PUTIH JANTAN GALUR WISTAR. JIFI [Internet]. 2022 Dec. 31 [cited 2024 Mar. 29];5(2):267-7. Available from: http://e-jurnal.stikes-isfi.ac.id/index.php/JIFI/article/view/1137