Jurnal Insan Farmasi Indonesia
type: channel
description: Jurnal Insan Farmasi Indonesia (JIFI) is a journal of pharmaceutical science published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin twice a year (May and December). The submitted articles must be unpublished and will be selected by the JIFI editor and reviewer team. JIFI is an open-access journal (P-ISSN: 2621-3184 & E-ISSN: 2621-4032) which means that all content is freely available without charge to the user. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. JOURNAL INFORMATION Journal Title: Jurnal Insan Farmasi Indonesia Initials: JIFI DOI: http://dx.doi.org/10.36387/jifi OAI Adress : https://e-jurnal.stikes-isfi.ac.id/index.php/JIFI/index Frequency: 2 issues per year
publisher: Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
language: en
publication name: Jurnal Insan Farmasi Indonesia
issn: 2621-3184
items: BEYOND THERAPEUTIC BENEFITS: KAJIAN FARMAKOVIGILANS EFEK SAMPING KORTIKOSTEROID DI INDONESIA
items: STUDI PENAMBATAN MOLEKUL SENYAWA METABOLIT SEKUNDER EKSTRAK AKAR TAWAR SERIBU (Bauhinia purpurea L) SEBAGAI POTENSI INHIBITOR α-Glukosidase
items: STUDI TENTANG PENGGUNAAN TUMBUHAN OBAT OLEH MASYARAKAT SUKU MUNA DI PULAU MUNA, SULAWESI TENGGARA
items: NARRATIVE REVIEW OF THE EFFECTIVENESS AND SAFETY OF ANTIRETROVIRAL THERAPY IN PATIENTS WITH HIV-HBV COINFECTION
items: UJI PENANGKAPAN RADIKAL DPPH DAN PENETAPAN KADAR FLAVONOID DARI DAUN KALANGKALA (Litsea garciae S. Vidal) EKSTRAK METANOL
items: ANALISIS HUBUNGAN TEKANAN DARAH DAN PENYAKIT PENYERTA TERHADAP KUALITAS HIDUP PASIEN HIPERTENSI
items: KETEPATAN PENGGUNAAN TURBUHALER DAN TINGKAT KONTROL ASMA PADA PASIEN ASMA: STUDI POTONG LINTANG DI RS X
items: ANALISIS KESESUAIAN PENYIMPANAN COLD CHAIN PRODUCT DI INSTALASI FARMASI RUMAH SAKIT ISLAM BANJARMASIN
items: EXPLORING THE ANTIBACTERIAL POTENTIAL OF RED MANGROVE APPLE LEAVES (SONNERATIA CASEOLARIS) AGAINST ACNE-CAUSING BACTERIA PROPIONIBACTERIUM ACNES
items: ANALISIS SENYAWA POLIFENOL DAN GLIKOSIDA PADA FRAKSI EKSTRAK ETANOL DAUN JAMBU METE (Anacardium occidentale L.) MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS
items: TLC FINGERPRINTING PROFILE AND FREE RADICAL SCAVENGING ACTIVITY (DPPH) OF METHANOL, ETHYL ACETATE, AND N-HEXANE FRACTIONS OF DADANGKAK LEAVES (Hydrolea spinosa L.)
items: ANALISIS HUBUNGAN TINGKAT KEPATUHAN PENGGUNAAN OBAT TERHADAP KUALITAS HIDUP PASIEN DIABETES MELLITUS TIPE II DI PUSKESMAS BAMBANGLIPURO BANTUL
items: OPTIMASI DAN EVALUASI FISIK FORMULA KAPSUL EKSTRAK SELEDRI DENGAN VARIASI BAHAN PENGISI
items: METABOLIT ANTIBAKTERI DARI Aspergilalus nidulans DSP 20, JAMUR ENDOFIT MANGROVE ASOSIASI Sesuvium portulacastrum
items: UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK BUNGA ROSELLA (Hibiscus sabdariffa L.) DAN KULIT BATANG KAYU MANIS (Cinnamomum burmannii) TERHADAP Escherichia coli
items: FORMULASI LOTION TABIR SURYA EKSTRAK ETANOL DAUN ANDONG MERAH (Cordyline Fruticosa (L.) A. Chev)
items: KAJIAN INTERAKSI OBAT PASIEN DIABETES MELITUS TIPE 2 DENGAN KOMORBID HIPERTENSI RAWAT JALAN DI RUMAH SAKIT AREA KOTA YOGYAKARTA
items: POTENSI ANTIPIRETIK DAN ANALGETIK EKSTRAK ETANOL KULIT BUAH PISANG KEPOK (Musa paradisiaca L. forma typica)
items: FORMULASI DAN UJI MUTU FISIK SEDIAAN LOTION DARI EKSTRAK DAUN NANAS (Ananas comosus (L).Merr)
items: ANALISIS JEJARING FARMAKOLOGI DAUN TEMBELEKAN (Lantana camara L.) TERHADAP ANTI LUKA BAKAR
items: INTERAKSI EKSTRAK DAUN TEH HIJAU DAN BUAH CABE MERAH SEBAGAI ANTIHIPERGLIKEMIA ANAK
items: UJI AKTIVITAS ANTIOKSIDAN PADA SERBUK SARI INSTAN DAUN PUDING HITAM (Graptophyllum Pictum L. Griff) MENGGUNAKAN METODE DPPH
items: ANALISIS PENGELOLAAN OBAT DI INSTALASI FARMASI RSUD. Dr. H. MOCH. ANSARI SALEH BANJARMASIN
items: TINGKAT KEPUASAN PASIEN DAN FAKTOR-FAKTOR YANG MEMPENGARUHI TERHADAP LAYANAN ANTAR OBAT (YANTARO) DEPO FARMASI RAWAT JALAN DI RSUD H. BADARUDDIN KASIM TABALONG
items: PROFIL KANDUNGAN FENOLIK DAN EVALUASI PARAMETER NON-SPESIFIK EKSTRAK ETANOL RIMPANG JAHE MERAH (Zingiber officinale var. rubrum)
items: STUDI PENGGUNAAN ANTIBIOTIK PADA PASIEN ULKUS DIABETIKUM DI INSTALASI RAWAT INAP RS X SEMARANG DENGAN PENDEKATAN ATC/DDD DAN DU 90%
items: EVALUASI AKTIVITAS ANTIBAKTERI SABUN VCO pH NETRAL TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli
items: FORMULASI SEDIAAN KRIM KOMBINASI EKSTRAK ETANOL MESOKARP SEMANGKA (Citrullus lanatus (Thunb.) dan BUAH TOMAT (Solanum lycopersicum L.) SEBAGAI TABIR SURYA
items: AKTIVITAS SITOTOKSIK EKSTRAK ETIL ASETAT DAUN AKAR KAIK-KAIK (Uncaria cordata (Lour.) Merr) PADA SEL KANKER SERVIKS HeLa
items: MOM IS HERO: PRENATAL-POSTNATAL CALENDAR SEBAGAI UPAYA PENCEGAHAN STUNTING DENGAN PENDEKATAN THEORY OF PLANNED BEHAVIOR

BEYOND THERAPEUTIC BENEFITS: KAJIAN FARMAKOVIGILANS EFEK SAMPING KORTIKOSTEROID DI INDONESIA
type: item
description: Corticosteroids are widely used in clinical practice in Indonesia for the treatment of various diseases. However, prolonged and/or high-dose corticosteroid therapy may lead to serious adverse effects that negatively affect patients’ quality of life. Monitoring of corticosteroid-related adverse drug reactions in Indonesia remains limited, highlighting the need for a pharmacovigilance approach to identify, assess, monitor, and prevent undesirable drug-related events. This review aimed to provide a comprehensive overview of adverse effects associated with corticosteroid use in Indonesia as a basis for safe, effective, and rational therapeutic decision-making. Literature searches were conducted through ScienceDirect, PubMed, Google Scholar, and manual searches using the keywords “pharmacovigilance,” “corticosteroid,” “side effect,” “adverse effect,” and “Indonesia” based on predefined inclusion and exclusion criteria. A total of eight eligible articles were critically analyzed, covering various corticosteroid dosage forms, patient characteristics, and the types and severity of adverse effects. The findings showed that adverse reactions ranged from mild to severe, with increased risk associated with long-term and high-dose corticosteroid use. This review emphasizes the importance of pharmacovigilance in improving healthcare professionals’ awareness and promoting rational corticosteroid use in Indonesia
subject: Articles
  topic: section
subject: Pharmacovigilance
  topic: keywords
subject: corticosteroids
  topic: keywords
subject: side effects
  topic: keywords
subject: Drug Rationale
  topic: keywords
subject: Indonesia
  topic: keywords
creator: Senya Puteri Amalia
creator: Farida Istiqamah
creator: Nur Ainah
creator: Desy Ayu Lestari
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 259
ending page: 273
doi: 10.36387/vv82rt22

STUDI PENAMBATAN MOLEKUL SENYAWA METABOLIT SEKUNDER EKSTRAK AKAR TAWAR SERIBU (Bauhinia purpurea L) SEBAGAI POTENSI INHIBITOR α-Glukosidase
type: item
description: Diabetes mellitus is a disease characterized by elevated blood glucose levels due to impaired insulin secretion or action. A therapeutic development strategy involves inhibiting the α-glucosidase enzyme. Bauhinia purpurea, L. is known to contain various compounds with potential antidiabetic activity. This study aims to investigate the potential of secondary metabolites from Bauhinia purpurea, L. extract as α-glucosidase inhibitors using an in silico molecular docking approach and ADMET prediction. Test compounds were obtained from LC-MS identification results, and their three-dimensional structures were downloaded from the PubChem database. The protein structure was obtained from the Protein Data Bank (PDB ID: 3L4W). The molecular docking process utilized the AutoDock Tools software, yielding a validation result of 1.9 Å. The results showed ΔG values ranging from -4.00 kcal/mol to -8.26 kcal/mol. ADMET prediction results indicated high HIA values >90%, Caco2 permeability in the low permeability category (<4 nm·s⁻¹), low BBB values, and AMES test results classified as non-mutagenic for all test compounds. Based on these results, the secondary metabolites contained in the Bauhinia purpurea, L. extract show potential as α-glucosidase inhibitors with favorable pharmacokinetic parameters, making them suitable for development into drug candidates through pharmaceutical or chemical structural modifications.
subject: Articles
  topic: section
subject: Bauhinia purpurea, L
  topic: keywords
subject: α-glukosidase
  topic: keywords
subject: molecular docking
  topic: keywords
subject: ADMET
  topic: keywords
subject: Phamaceutical pharmacy
  topic: disciplines
creator: Nurul Fajeriyati
creator: Rizka Mulya Miranti
creator: Yulianita Pratiwi Indah Lestari
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 244
ending page: 258
doi: 10.36387/kmrfn388

STUDI TENTANG PENGGUNAAN TUMBUHAN OBAT OLEH MASYARAKAT SUKU MUNA DI PULAU MUNA, SULAWESI TENGGARA
type: item
description: The use of medicinal plants still plays an important role in traditional medicine practices in Indonesia, including in the Muna Tribe on Muna Island, Southeast Sulawesi. This research aims to identify the types of medicinal plants used, the parts of the plants used, the processing methods, and the types of diseases treated based on the local genius of the community. The research method used was snowball sampling technique, with data collection through interviews with the Muna Tribe using questionnaires. The question includes information about the type of disease, herb or single plant used, local name, part used, and the method of treatment. Each mentioned plant is then identified through a determination process to obtain its Latin name, and is documented in the form of a herbarium. The results of the study show that Muna Tribe on Muna Island, Southeast Sulawesi Province, has used as many as 29 plant species from 18 families as medicinal ingredients. The most dominant part of the plant used is the leaves. The most common method of using plants or herbs is boiled, the boiled water is drunk. This method is the most commonly applied practice by the local community in using plants as traditional medicine.
subject: Articles
  topic: section
subject: Ethnomedicine
  topic: keywords
subject: Local genius
  topic: keywords
subject: Traditional herbs
  topic: keywords
subject: Muna tribe
  topic: keywords
creator: Rimala Sanipurnama Kindkasman
creator: Djoko Santosa
creator: Nanang Fakhrudin
creator: Akhmad Riski
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 230
ending page: 243
doi: 10.36387/vpdg3a81

NARRATIVE REVIEW OF THE EFFECTIVENESS AND SAFETY OF ANTIRETROVIRAL THERAPY IN PATIENTS WITH HIV-HBV COINFECTION
type: item
description: HIV-HBV coinfection remains a major global health challenge associated with increased morbidity and mortality. Various studies have evaluated the effectiveness and safety of antiviral therapies in coinfected patients; however, the findings remain inconsistent. This narrative review aimed to summarize the current evidence regarding the effectiveness and safety of antiretroviral therapy in patients with HIV-HBV coinfection. Literature searches were conducted through PubMed and Google Scholar for studies published between 2014 and 2025 using keywords related to HIV, hepatitis B, nucleos(t)ide analogues, interferon alfa, effectiveness, and safety. The findings demonstrated that the TLD regimen (tenofovir, lamivudine, and dolutegravir) showed superior virological outcomes compared with TLE (tenofovir, lamivudine, and efavirenz), including higher viral suppression rates and greater CD4 cell recovery. Nucleos(t)ide analogues such as entecavir and telbivudine effectively reduced HBV DNA levels and improved liver function markers. However, several adverse drug reactions were reported, including dizziness, nausea, vomiting, metabolic disturbances, and renal impairment, particularly with tenofovir-containing regimens. Interferon alfa also demonstrated potential benefits in enhancing seroconversion. Overall, TLD is considered the preferred regimen due to its superior efficacy and resistance profile, although careful monitoring for adverse effects remains essential.
subject: Articles
  topic: section
subject: Hepatitis B
  topic: keywords
subject: HIV
  topic: keywords
subject: Interferon alfa
  topic: keywords
subject: Nucleos(t)ide analogues
  topic: keywords
subject: Clinical Pharmacy
  topic: disciplines
creator: Rizky Yuliatus Solicha
creator: Vitarani Dwi Ananda Ningrum
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 215
ending page: 229
doi: 10.36387/phqp4b95

UJI PENANGKAPAN RADIKAL DPPH DAN PENETAPAN KADAR FLAVONOID DARI DAUN KALANGKALA (Litsea garciae S. Vidal) EKSTRAK METANOL
type: item
description: Excessive free radicals the body can induce oxidative stress, which plays a significant role the development of various degenerative diseases. Therefore, the search for natural sources antioxidants essential to mitigate detrimental effects free radicals on health. This study aimed determine flavonoid content and evaluate the free radical scavenging activity using DPPH method the methanolic extract Litsea garciae (kalangkala) leaves. Extraction was carried out using methanol as the solvent, followed by thin-layer chromatography (TLC) analysis flavonoid identification and determination total flavonoid content using a spectrophotometric method with quercetin the standard. Antioxidant activity was assessed using DPPH assay, with the IC₅₀ value used an indicator of free radical scavenging effectiveness. The TLC results showed similar Rf values between the extract and quercetin, indicating the presence flavonoids in kalangkala leaves. The total flavonoid content was recorded as 8.3364 ± 0.0023 mg quercetin equivalents/g extract, while the DPPH assay yielded an IC₅₀ value 141.144 μg/mL with RSD of 2.333%, which was higher than that quercetin (6.101 μg/mL with RSD of 1.450%). These findings indicate that methanolic extract of Litsea garciae leaves exhibits moderate antioxidant activity and has potential a natural antioxidant source. Therefore, kalangkala leaves may be further developed for prevention of oxidative stress.
subject: Articles
  topic: section
subject: L. garciae
  topic: keywords
subject: TLC
  topic: keywords
subject: Flavonoids
  topic: keywords
subject: Antioxidant Activity
  topic: keywords
creator: Najwa Rahmadina
creator: Rizka Aulia Ramadani
creator: Samsul Hadi
creator: Nahdiati Ulfah
creator: Noor Rahmi Febriani
creator: Nor Khadijah
creator: Erika Indriani
creator: Nanda Hesti Rahmawati
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 94
ending page: 104
doi: 10.36387/j4mds879

ANALISIS HUBUNGAN TEKANAN DARAH DAN PENYAKIT PENYERTA TERHADAP KUALITAS HIDUP PASIEN HIPERTENSI
type: item
description: Hypertension is a chronic condition that may reduce patients’ quality of life, particularly when accompanied by uncontrolled blood pressure and comorbid diseases. This study aimed to assess the quality of life of patients with hypertension and to analyze the relationship between blood pressure, comorbidities, and quality of life. A cross-sectional study design was used, with prospective data collection using the SF-6D instrument. A total of 305 respondents who visited the North Banjarmasin Public Health Center and met the inclusion criteria were selected using consecutive sampling. Quality of life was calculated using the SF-6D index calculator, while the relationship between variables was analyzed using the Pearson Chi-Square test. The results showed that the mean utility score of hypertensive patients receiving treatment was 0.7835. Statistical analysis indicated a significant association between quality of life and blood pressure, with p=0.016, as well as between quality of life and comorbidities, with p=0.037. Therefore, blood pressure and comorbidities are associated with the quality of life of patients with hypertension.
subject: Articles
  topic: section
subject: Utility
  topic: keywords
subject: Instrumen SF-6D
  topic: keywords
subject: Chi-square
  topic: keywords
subject: Hypertension
  topic: keywords
subject: farmasi komunitas
  topic: disciplines
creator: Abdul Mahmud Yumassik
creator: Muhammad Faqih
creator: Fitrah Shafran Ilahi
creator: Nordin
creator: Anshar Timur Samudra
creator: Noor Aisyah
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 207
ending page: 214
doi: 10.36387/xfx5f967

KETEPATAN PENGGUNAAN TURBUHALER DAN TINGKAT KONTROL ASMA PADA PASIEN ASMA: STUDI POTONG LINTANG DI RS X
type: item
description: Asthma is a chronic inflammatory disease requiring long-term inhalation therapy. Treatment success depended on both the prescribed medication and the correct use of the inhaler. This study aimed to evaluate the accuracy of the Turbuhaler technique and its association with asthma control. A prospective cross-sectional study was conducted among 39 adult outpatients using a Turbuhaler at a hospital in Yogyakarta, Indonesia. Inhaler technique was evaluated using a checklist, and asthma control was assessed with the Asthma Control Test (ACT). The association was analyzed using Fisher's exact test. The results showed that 76.92% of patients used the Turbuhaler incorrectly and that 79.49% did not achieve asthma control. A significant association was found between correct technique and asthma control (p < 0.001), with a prevalence ratio of 9.00 (95% confidence interval [CI], 1.42–57.12). Patients who performed the technique correctly were nine times more likely to achieve control. The most frequently missed steps were holding one's breath after inhaling, rinsing one's mouth, and taking a deep breath. Correct Turbuhaler technique is a key determinant of asthma control. Pharmacist-led education focusing on these critical steps is essential to optimize treatment outcomes and prevent adverse effects.
subject: Articles
  topic: section
subject: Asthma
  topic: keywords
subject: ACT
  topic: keywords
subject: Asthma control
  topic: keywords
subject: Inhaler technique
  topic: keywords
subject: Turbuhaler
  topic: keywords
creator: Sri Suprapti
creator: Nurul Kusumawardani
creator: Rizal Fauzi
creator: Ishak
creator: Fitriah Ramadani
creator: Widhowati Destiathree Supardi
creator: Emelda
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 195
ending page: 206
doi: 10.36387/s8n1n127

ANALISIS KESESUAIAN PENYIMPANAN COLD CHAIN PRODUCT DI INSTALASI FARMASI RUMAH SAKIT ISLAM BANJARMASIN
type: item
description: CCPs are pharmaceutical preparations that require strict temperature control to maintain drug stability. Temperature deviations during storage cause degradation of pharmaceutical product quality. This study aims to analyze the compliance of the CCP storage system based on the five indicators of the CDOB standard as stipulated in BPOM Regulation No. 20 of 2025. The study used a descriptive observational design with a cross-sectional approach through direct observation using standardized observation sheets. Data were analyzed descriptively qualitatively and quantitatively by calculating the percentage of compliance, and the data were processed using Microsoft Excel 2021. The results showed that the compliance level of CCP storage in the Banjarmasin Islamic Hospital Pharmacy Unit was 90.48%, in accordance with the 2025 CDOB BPOM regulations. Temperature monitoring and human resource quality and capacity were fully compliant (100%), building and space systems (87.5%), facilities and infrastructure (75%), and documentation and reporting (87.5%). Non-compliance was influenced by several factors, including limited storage space, the absence of temperature alarms, refrigerator placement that did not meet standard distances, and evidence of equipment calibration. Overall, CCP storage in the pharmacy installation did not fully meet CDOB standards, requiring improvements in infrastructure, completeness of documentation, and optimization of storage space management.
subject: Articles
  topic: section
subject: Analysis
  topic: keywords
subject: Storage Compliance
  topic: keywords
subject: CCP
  topic: keywords
creator: Muhammad Fadhil Qadhafi
creator: Amaliyah Wahyuni
creator: Noor Aisyah
creator: Hidayaturrahman
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 140
ending page: 153
doi: 10.36387/1s92jd86

EXPLORING THE ANTIBACTERIAL POTENTIAL OF RED MANGROVE APPLE LEAVES (SONNERATIA CASEOLARIS) AGAINST ACNE-CAUSING BACTERIA PROPIONIBACTERIUM ACNES
type: item
description: Acne that appears on the face can cause changes in the form of swelling, redness, pus and cause pain so that it will cause an impression that is less attractive in appearance and affects beauty. One of the causes of acne is due to the activity of Propionibacterium acnes bacteria. Pidada Merah leaves are one of the plants that contain antibacterial compounds. It is said to contain compounds as antibacterial because it contains secondary metabolites including flavonoids, alkaloids, tannins, saponins, and phenols. The purpose of this study was to determine the antibacterial activity and the diameter of the inhibition zone of Pidada Merah leaf extract against the growth of Propionibacterium acnes.This type of research is not experimental using the well method. This study was divided into seven groups; the extract group with various concentrations (20%, 40%, 60%, and 80%), the positive control group (clindamycin 0.1%) and the negative control group (Aquadest). The results showed that the Pidada Merah leaf extract had antibacterial activity against the growth of Propionibacterium acnes. The diameter of the inhibition zone formed at concentrations of 20%, 40%, 60%, and 80%, respectively 11.51 mm (strong), 11.73 mm (strong), 12 mm (strong), 12.4 mm (strong).
subject: Articles
  topic: section
subject: Propionibacterium acnes
  topic: keywords
subject: Sonneratia caseolaris
  topic: keywords
subject: Inhibitions Zone
  topic: keywords
subject: bahan alam
  topic: disciplines
creator: Eka Kumalasari
creator: Rizki Arianto
creator: Dwi Rizki Febrianti
creator: Novia Ariani
creator: Muhammad Ma'ruf
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 183
ending page: 194
doi: 10.36387/v1f3zg64

ANALISIS SENYAWA POLIFENOL DAN GLIKOSIDA PADA FRAKSI EKSTRAK ETANOL DAUN JAMBU METE (Anacardium occidentale L.) MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS
type: item
description: Cashew leaves (Anacardium occidentale L.) are known to contain secondary metabolites with potential medicinal properties, including polyphenols and glycosides. This study aimed to determine the qualitative and quantitative contents of polyphenol and glycoside compounds in the ethanol extract fractions of cashew leaves using the UV-Vis spectrophotometric method. Cashew leaves were extracted using 96% ethanol. Fractionation was carried out using n-hexane and ethyl acetate solvents. Glycoside content was determined using quercetin as the standard at a wavelength of 430 nm, while polyphenol content was determined using gallic acid as the standard at a wavelength of 700 nm. Qualitative test results showed that both n-hexane and ethyl acetate fractions were positive for glycosides, indicated by a green color, and positive for polyphenols, indicated by a greenish-purple color. Quantitative results showed that the glycoside content in the n-hexane fraction was 3.999 mgQE/g and in the ethyl acetate fraction was 8.043 mgQE/g. The polyphenol content in the n-hexane fraction was 2.138 mgGAE/g and in the ethyl acetate fraction was 3.198 mgGAE/g. The ethyl acetate fraction exhibited higher glycoside and polyphenol contents compared to the n-hexane fraction.
subject: Articles
  topic: section
subject: Cashew Leaves
  topic: keywords
subject: Glycosides
  topic: keywords
subject: Polyphenols
  topic: keywords
subject: Fractionation
  topic: keywords
subject: UV-Vis Spectrophotometri
  topic: keywords
subject: Bahan alam dan kosmetik
  topic: disciplines
creator: Rabiatul Adawiyah
creator: Evita Wulandari
creator: Nur Ani
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 165
ending page: 172
doi: 10.36387/cjs1d853

TLC FINGERPRINTING PROFILE AND FREE RADICAL SCAVENGING ACTIVITY (DPPH) OF METHANOL, ETHYL ACETATE, AND N-HEXANE FRACTIONS OF DADANGKAK LEAVES (Hydrolea spinosa L.)
type: item
description: Dadangkak leaves (Hydrolea spinosa L.) contain various secondary metabolites with potential antioxidant activity. This study aimed to evaluate the thin-layer chromatography (TLC) fingerprinting profile and antioxidant activity of the n-hexane, ethyl acetate, and methanol fractions of Dadangkak leaf extract. Extraction was performed using ethanol followed by fractionation based on solvent polarity. Compound profiling was analyzed by TLC under UV light at 254 and 366 nm using several spray reagents. Antioxidant activity was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method with UV-Vis spectrophotometric measurement at 517 nm to determine IC₅₀ values. The results demonstrated that the methanol fraction exhibited the most comprehensive chromatographic profile, showing positive responses to all spray reagents, indicating a higher diversity of secondary metabolites compared with the other fractions. All fractions showed free radical scavenging activity against DPPH radicals. The IC₅₀ values were 0.110 ppm for the n-hexane fraction, 0.245 ppm for the ethyl acetate fraction, and −1.588 ppm for the methanol fraction. Furthermore, the methanol fraction showed the highest coefficient of determination (R²), indicating the strongest linear relationship between concentration and inhibition percentage. These findings suggest that the methanol fraction possesses the greatest potential as a natural antioxidant source.
subject: Articles
  topic: section
subject: IC₅₀
  topic: keywords
subject: Hydrolea spinosa L.
  topic: keywords
subject: fractionation
  topic: keywords
subject: antioxidant
  topic: keywords
subject: DPPH
  topic: keywords
subject: TLC
  topic: keywords
subject: IC50
  topic: keywords
creator: Dwi Rizki Febrianti
creator: Desy Ayu Lestari
creator: Rakhmadhan Niah
creator: Eka Kumalasari
creator: Inderiyani
creator: Novia Ariani
creator: Subagus Wahyuono
creator: Siska Musiam
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 173
ending page: 182
doi: 10.36387/4r6vja90

ANALISIS HUBUNGAN TINGKAT KEPATUHAN PENGGUNAAN OBAT TERHADAP KUALITAS HIDUP PASIEN DIABETES MELLITUS TIPE II DI PUSKESMAS BAMBANGLIPURO BANTUL
type: item
description: Diabetes Mellitus is a degenerative disease that requires long-term management. Medication adherence plays an important role in treatment success, as it can influence the quality of life in patients with Type II Diabetes Mellitus. This study aimed to determine the relationship between medication adherence and quality of life among Type II Diabetes Mellitus patients at Bambanglipuro Primary Health Center, Bantul. This study used an analytical observational design with a cross-sectional approach. A total of 52 patients were included using total sampling technique. Medication adherence was measured using the Morisky Medication Adherence Scale (MMAS-8), while quality of life was assessed using the Short Form-36 (SF-36). Data were analyzed using the Chi-Square test. The results showed that most respondents had high medication adherence (86.54%) and good quality of life across most domains. The Chi-Square test showed a significance value of p = 0.000 (p < 0.05), indicating a significant relationship between medication adherence and quality of life. In conclusion, there is a significant relationship between medication adherence and quality of life in patients with Type II Diabetes Mellitus.
subject: Articles
  topic: section
subject: Medication Adherence
  topic: keywords
subject: Quality of Life
  topic: keywords
subject: Type II Diabetes Mellitus
  topic: keywords
subject: MMAS-8
  topic: keywords
subject: SF-36
  topic: keywords
creator: Mexsi Mutia Rissa
creator: Machfudz Eko Arianto
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 154
ending page: 164
doi: 10.36387/4678wd55

OPTIMASI DAN EVALUASI FISIK FORMULA KAPSUL EKSTRAK SELEDRI DENGAN VARIASI BAHAN PENGISI
type: item
description: Celery has the activity as an antihypertensive. Celery extract contains apigenin which can lower blood pressure by preventing the narrowing of blood vessels. Celery extract can be formulated in capsule. One of the important components in making capsules is the filler. Filler can increase the mass of capsule and reduce the moisture of the extract in the capsule. The purpose of this study is to determine the optimal filler for celery extract capsules. In this study, a physical evaluation of celery extract capsules was carried out with 4 types of fillers, such as Manihot starch, Flocel 101, Lactose, and Corn starch amount 37% for each variation. The observed evaluations was the organoleptic properties, moisture content, disintegration time, uniformity and hygroscopicity. Each evaluation was analyzed by Graphpad ANOVA Tukey Multiple comparation. The optimum physical evaluation result was the corn starch capsule filler with a flow time of 20,0 grams/sec, the water content of 7,88% and the disintegration time of 9,26 minute, the weight uniformity met the requirements also the physical appearance with no lumps before an after exposure for 24 hours. Thus corn starch can be an optimal filler in celery extract capsule preparation.
subject: Articles
  topic: section
subject: Filler
  topic: keywords
subject: optimation
  topic: keywords
subject: Celery
  topic: keywords
subject: Evaluation
  topic: keywords
subject: Capsule
  topic: keywords
subject: Extract
  topic: keywords
subject: teknologi farmasi bahan alam
  topic: disciplines
creator: Joko Kawiyanto
creator: Alifah Asri Elina
creator: Margaretha Harnanda Putri
creator: Puji Hartati
creator: Galuh Saras Sukmaningrum
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 126
ending page: 139
doi: 10.36387/jifi.v9i1.3007

METABOLIT ANTIBAKTERI DARI Aspergilalus nidulans DSP 20, JAMUR ENDOFIT MANGROVE ASOSIASI Sesuvium portulacastrum
type: item
description: Mangrove-associated endophytic fungi are promising producers of antibacterial secondary metabolites. This study evaluated the potential of Aspergillus nidulans DSP 20, isolated from leaves of Sesuvium portulacastrum collected from the Sekotong mangrove-associated ecosystem, as a producer of antibacterial metabolites. The isolate was obtained through surface sterilization of leaf tissue, colony purification, and morphological characterization. Metabolite production was performed by 21-day solid-state fermentation followed by ethyl acetate extraction. The metabolite profile was qualitatively analyzed using thin-layer chromatography, while antibacterial activity was tested against Staphylococcus aureus and Escherichia coli using the disc diffusion method. DSP 20 showed morphological characteristics supporting its identification as A. nidulans, produced an ethyl acetate extract with several chromatographic spots, and formed inhibition zones against both test bacteria. These findings indicate that A. nidulans DSP 20 is a potential preliminary source of antibacterial metabolites from mangrove-associated endophytic fungi.
subject: Articles
  topic: section
subject: antibacterial activity
  topic: keywords
subject: Aspergillus nidulans
  topic: keywords
subject: endophytic fungi
  topic: keywords
subject: mangrove association
  topic: keywords
subject: secondary metabolite
  topic: keywords
subject: Sesuvium portulacastrum
  topic: keywords
subject: Biologi farmasi
  topic: disciplines
subject: Mikrobiologi Farmasi
  topic: disciplines
creator: Safwan Safwan
creator: Baiq Desti Isnanda Maolia
creator: Yuli Fitriana
creator: Abdul Rahman Wahid
creator: Widayatul Khairi
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 119
ending page: 125
doi: 10.36387/safz8j78

UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK BUNGA ROSELLA (Hibiscus sabdariffa L.) DAN KULIT BATANG KAYU MANIS (Cinnamomum burmannii) TERHADAP Escherichia coli
type: item
description: Escherichia coli is one of the main causes of diarrhea; therefore, alternative antibacterial agents derived from natural materials are needed. Roselle flowers (Hibiscus sabdariffa L.) and cinnamon bark (Cinnamomum burmannii) are known to possess antibacterial activity through different mechanisms of action. This study aimed to determine and compare the antibacterial activity of 30% roselle flower extract, 10% cinnamon bark extract, and their combination against Escherichia coli. The theoretical basis of this study was the flavonoid content in roselle and the cinnamaldehyde and eugenol compounds in cinnamon as antibacterial agents. This research was an experimental study using the disk diffusion method with three treatment groups and one negative control group. The observed parameter was the diameter of the inhibition zone after 24 hours of incubation at 37°C. The results showed that all treatment groups produced inhibition zones in the moderate category, while the negative control did not produce any inhibition zone. Statistical analysis using the Kruskal Wallis test showed a significant difference in antibacterial activity among the groups (Asymp.Sig = 0.000008). Further analysis using the Mann Whitney test showed that the combination extract had the highest antibacterial activity.
subject: Articles
  topic: section
subject: Antibacteria
  topic: keywords
subject: Diarrhea
  topic: keywords
subject: Escherichia coli
  topic: keywords
subject: Cinnamon
  topic: keywords
subject: Roselle
  topic: keywords
subject: Mikrobiologi Farmasi
  topic: disciplines
creator: Muhammad Irsyad Ilham
creator: Naomi Dwi Cahyanti
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 105
ending page: 118
doi: 10.36387/1pbmdb49

FORMULASI LOTION TABIR SURYA EKSTRAK ETANOL DAUN ANDONG MERAH (Cordyline Fruticosa (L.) A. Chev)
type: item
description: Ethanol extract of the of red andong leaves has strong antioxidant activity and has the potential to be a sunscreen with maximum protection. This study aims to formulate and evaluate the sunscreen activity of a lotion preparation made from ethanol extract of red andong leaves. The sunscreen activity test was carried out using the UV-Vis spectrophotometer method with a wavelength of 290-320 nm. The ethanol extract of the red andong leaves is formulated in lotions with various concentrations (F1: 5%, F2: 10%, F3: 15%). The lotion was tested for physical properties including organoleptic, viscosity, dispersibility, pH, homogeneity, type of lotion, and protection ability. The results showed that the ethanol extract of red andong leaves can be formulated into lotion preparations, where the three lotion formulas with variations in the concentration of 5%, 10%, and 15% of the red andong leaf extract ethanol produce light brown, the distinctive odor, semi-solid, a homogeneous, M/A type emulsion, meets the requirements of pH, viscosity, dispersibility, and provides protection. The results of the sunscreen activity test were respectively 9,81±0,10; 12,15±0,25; 14,03±0,53, with the highest SPF value being 14,03±0,53 in formula III (15% red andong ethanol extract) which is included in the maximum protection category.
subject: Articles
  topic: section
subject: Formulasi
  topic: keywords
subject: Tabir Surya
  topic: keywords
subject: Ekstrak Etanol Daun Andong Merah
  topic: keywords
subject: Lotion
  topic: keywords
subject: Akademi Farmasi Yarsi Pontianak
  topic: disciplines
creator: Weni Puspita
creator: Heny Puspasari
creator: Ika Ristia Rahman
creator: Dian Kartika Sari
creator: Inderiyani
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 81
ending page: 93
doi: 10.36387/m82fby98

KAJIAN INTERAKSI OBAT PASIEN DIABETES MELITUS TIPE 2 DENGAN KOMORBID HIPERTENSI RAWAT JALAN DI RUMAH SAKIT AREA KOTA YOGYAKARTA
type: item
description: Patients with type 2 diabetes mellitus and hypertension comorbidity generally receive more than one medication, increasing the risk of drug interactions that may affect therapeutic outcomes. This study aimed to determine the potential drug interactions in outpatients with type 2 diabetes mellitus and hypertension at PKU Muhammadiyah Gamping Hospital during January–December 2024. This research employed a descriptive-retrospective observational method using 44 medical records selected through purposive sampling based on inclusion and exclusion criteria. Drug interactions were assessed using the MedFacts Pocket Guide of Drug Interactions, Stockley’s Drug Interactions (2009), and drug interaction checkers from Medscape and Drugs.com based on interaction mechanisms and severity levels. The results showed 129 cases of drug interactions, with the most common combination being metformin–amlodipine (10 cases; 7.7%). The most frequent interaction mechanism was pharmacodynamic interaction (68 cases; 52.71%), while the severity level was predominantly moderate according to Medscape (65 cases; 50.38%) and Drugs.com (79 cases; 61.24%). Major interactions were identified in the bisoprolol fumarate–clonidine combination (4 cases; 5.3%). This study indicates the potential for drug interactions in antidiabetic and antihypertensive therapy, highlighting the need for therapeutic monitoring and dose adjustment to improve treatment safety and effectiveness.
subject: Articles
  topic: section
subject: Diabetes Melitus
  topic: keywords
subject: Hipertensi
  topic: keywords
subject: Interaksi Obat
  topic: keywords
subject: Clinical Pharmacy
  topic: disciplines
creator: Ginanjar Zukhruf Saputri
creator: Siti Anisya Rahayu
creator: Endang Darmawan
creator: Prita Anggraini
creator: Woro Supadmi
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 66
ending page: 80
doi: 10.36387/07k2bp37

POTENSI ANTIPIRETIK DAN ANALGETIK EKSTRAK ETANOL KULIT BUAH PISANG KEPOK (Musa paradisiaca L. forma typica)
type: item
description: Nyeri merupakan gejala yang menunjukkan adanya gangguan dalam tubuh, sedangkan demam (febris) adalah kondisi yang sering dialami masyarakat dan memerlukan penanganan untuk menurunkan suhu tubuh melalui pemberian antipiretik. Kulit buah pisang kepok (Musa paradisiaca L. forma typica) mengandung senyawa metabolit sekunder berupa alkaloid, flavonoid, tanin, dan saponin yang berpotensi memiliki aktivitas sebagai analgetik dan antipiretik. Penelitian ini bertujuan untuk mengetahui daya analgetik dan antipiretik dari ekstrak etanol kulit buah pisang kepok. Penelitian ini adalah eksperimental yang menggunakan hewan uji mencit jantan yang terdiri dari kelompok kontrol negatif Na-CMC 0,5%, kelompok kontrol positif asam mefenamat sebagai analgetika dan parasetamol sebagai aintipiretika, kelompok ekstrak dosis 1 (500 mg/kgBB), dosis 2 (1000 mg/kgBB) dan dosis 3 (1500 mg/kgBB). Induksi nyeri menggunakan asam asetat 1% sedangkan induksi demam menggunakan pepton 5% Pengamatan dilakukan setiap 30 menit selama 120 menit. Hasil didapatkan daya analgetik dari ekstrak kulit buah pisang kepok secara urutan dosis yaitu 67,54%, 69,18% dan 69,57% sedangkan daya antipretika yaitu 0,52%, 0,82% dan 0,83%.
subject: Articles
  topic: section
subject: Kepok banana peel
  topic: keywords
subject: Musa paradisiaca
  topic: keywords
subject: Analgetic
  topic: keywords
subject: antipyretic
  topic: keywords
subject: in vivo
  topic: keywords
subject: Farmakologi dan bahan alam
  topic: disciplines
creator: Novia Ariani
creator: Irina Yolanda
creator: Dhea Misrina Salsabila
creator: Dwi Rizki Febrianti
creator: Pra Panca Bayu Chandra
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 428
ending page: 439
doi: 10.36387/jifi.v8i2.2892

FORMULASI DAN UJI MUTU FISIK SEDIAAN LOTION DARI EKSTRAK DAUN NANAS (Ananas comosus (L).Merr)
type: item
description: Pineiapplei leiaveis (Ananas comosuis (L.) Meirr) is known as a natuiral ingreidieint that contains variouis bioactivei compouinds with thei poteintial for antioxidant activity, so it has thei opportuinity to bei uiseid in thei deiveilopmeint of topical cosmeitic preiparations. This reiseiarch aims to deiveilop a lotion formuilation that contains pineiapplei leiaf eixtract and asseiss thei physical quiality of thei reisuilting preiparation. Thei eixtraction proceiss is carrieid ouit by maceiration meithod uising 70% eithanol solveint and produiceis a yieild of 7,028%. Lotion is formuilateid in threiei variations, nameily F0 withouit thei addition of eixtract as a control, F1 with 1% eixtract conceintration, and F2 with 3% conceintration. Physical quiality teisting incluideis pH eivaluiation, organoleiptic propeirtieis, spreiadability, viscosity, and homogeineiity. Phytocheimical screieining reisuilts show thei preiseincei of flavonoid compouinds, alkaloids, and tannins in pineiapplei leiaf eixtract. Thei eintirei formuila meieits thei physical quiality reiquiireimeints of topical preiparations, shown by a pH valuiei that is suiitablei for thei skin condition, spreiading poweir and viscosity that meieits thei standard, as weill as good homogeineiity withouit phasei seiparation. Thei addition of pineiapplei leiaf eixtract doeis not reiduicei thei physical stability of thei preiparation, so it has thei poteintial to bei fuirtheir deiveilopeid as a natuiral activei ingreidieint in skin carei lotion formuilations.
subject: Articles
  topic: section
subject: Pineiapplei leaves
  topic: keywords
subject: Lotion
  topic: keywords
subject: Physical quality
  topic: keywords
subject: D3 farmasi
  topic: disciplines
creator: Cikra Ikhda Nur Hamidah Safitri
creator: Qholindah Qumairo Vidya Zahra
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 54
ending page: 65
doi: 10.36387/jifi.v9i1.2888

ANALISIS JEJARING FARMAKOLOGI DAUN TEMBELEKAN (Lantana camara L.) TERHADAP ANTI LUKA BAKAR
type: item
description: Burn injuries are skin lesions that can cause tissue damage, infection, and impaired regeneration if not properly treated. Lantana camara L. leaves are known to contain various secondary metabolites with potential wound-healing properties. This study aimed to analyze the anti-burn potential of Lantana camara using a network pharmacology approach. Computational analyses were performed using the KNApSACK, SwissADME, SwissTargetPrediction, GeneCards, STRING-DB, Cytoscape–CytoHubba, and ShinyGO 0.77 databases. A total of 39 secondary metabolites were identified, all of which fulfilled Lipinski’s Rule of Five, indicating good potential oral bioavailability. Protein target analysis revealed 305 intersecting proteins between metabolite targets and burn-related proteins. Network analysis identified AKT1 as the main hub protein, followed by TNF, IL6, STAT3, BCL2, HIF1A, and EGFR. The major biological pathways involved included the PI3K/Akt and HIF-1 signaling pathways, which regulate cell proliferation, angiogenesis, anti-apoptosis, and hypoxia response. In addition, positive regulation of peptidyl-serine phosphorylation was identified as the dominant biological process associated with inflammation regulation and tissue regeneration. These findings suggest that Lantana camara has strong potential as an anti-burn agent through a multitarget mechanism that supports tissue healing.
subject: Articles
  topic: section
subject: Tembelekan leave
  topic: keywords
subject: Lantana camara
  topic: keywords
subject: Network pharmacology
  topic: keywords
creator: Tri Diana Puspita Rini
creator: Wardah Salsabila Rafli
creator: Rissa Maharani Dewi
creator: Meki Pranata
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 41
ending page: 53
doi: 10.36387/p32xd546

INTERAKSI EKSTRAK DAUN TEH HIJAU DAN BUAH CABE MERAH SEBAGAI ANTIHIPERGLIKEMIA ANAK
type: item
description: Diabetes mellitus is a condition in which blood sugar levels are very high and cannot be controlled for an extended period. Therefore, more effective alternative treatments are needed. One of the materials being studied is green tea leaves (Camellia sinensis L) and red chili peppers (Capsicum annuum L), both of which are known to have antihyperglycemic effects. This study aims to determine the interaction between green tea leaf extract and red chili pepper extract in reducing blood glucose levels in mice with elevated blood sugar. A total of 25 mice were used and divided into 5 groups, each containing 5 mice. In the treatment, groups were given green tea leaf extract at a dose of 37.5 mg per 30 grams of body weight per day, red chili pepper extract at 12.5 mg per 30 grams of body weight per day, and metformin as a comparison at a dose of 169 mg per gram for 1 to 6 days or until blood glucose levels decreased. The parameter observed was the decrease in blood glucose levels. The results showed that the administration of green tea leaf extract and red chili pepper extract could significantly reduce blood glucose levels in mice.
subject: Articles
  topic: section
subject: antihyperglycemia
  topic: keywords
subject: green tea
  topic: keywords
subject: red chili pepper
  topic: keywords
subject: Farmasi klinis dan komunitas
  topic: disciplines
creator: Cikra Ikhda Nur Hamidah Safitri
creator: Dewi Anjar Wati
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 427
ending page: 436
doi: 10.36387/jifi.v8i2.2863

UJI AKTIVITAS ANTIOKSIDAN PADA SERBUK SARI INSTAN DAUN PUDING HITAM (Graptophyllum Pictum L. Griff) MENGGUNAKAN METODE DPPH
type: item
description: Instant beverages are an innovation in herbal products that are practical, easy to serve, and have a longer shelf life compared to liquid preparations, making them widely developed as health drinks. Black pudding leaves (Graptophyllum pictum L. Griff) are known to contain flavonoid compounds that act as antioxidants and have the potential to be processed into instant beverages. This study aimed to evaluate the antioxidant activity of instant pollen powder from black pudding leaves using the DPPH method and to determine the IC₅₀ value as an indicator of antioxidant strength. The preparations were made in three formulations with concentrations of 20%, 30%, and 50%. The results showed that all formulations exhibited very strong antioxidant activity, with IC₅₀ values of 16.827 ppm (F1), 16.375 ppm (F2), and 7.713 ppm (F3). All IC₅₀ values were within the very active category (IC₅₀ < 50 ppm). These findings indicate that instant pollen powder of black pudding leaves has great potential to be developed as a natural antioxidant source in the form of a functional herbal drink that is not only easy to consume but also beneficial in helping protect the body against free radical damage.
subject: Articles
  topic: section
subject: Antioxidants
  topic: keywords
subject: DPPH
  topic: keywords
subject: IC50
  topic: keywords
subject: Instant pollen powder
  topic: keywords
subject: Graptophyllum pictum
  topic: keywords
subject: Analisis Farmasi
  topic: disciplines
creator: Herlina
creator: Anisa Agustina
creator: Tri Yanuarto
creator: Elly Mulyani
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 407
ending page: 417
doi: 10.36387/jifi.v8i2.2856

ANALISIS PENGELOLAAN OBAT DI INSTALASI FARMASI RSUD. Dr. H. MOCH. ANSARI SALEH BANJARMASIN
type: item
description: Optimal drug management is essential because stock shortages or surpluses can affect hospital service costs. This study aimed to determine the percentage of planning achievement, invoice errors, procurement frequency per drug item, and the percentage of dead stock, expired, and damaged drugs at Dr. H. Moch Ansari Saleh Regional General Hospital, Banjarmasin. This study was a descriptive, observational, non-experimental research with a cross-sectional design using retrospective data, analyzed quantitatively and presented descriptively. The population consisted of all pharmaceutical supply management data from 2024. Samples were obtained using a total sampling technique, covering data on planning, procurement, receipt, storage, and control. Observation sheets were used as instruments, and data were processed using Microsoft Excel. The results showed a planning achievement rate of 86.06%. Invoice errors were 0%, meeting the standard. Out of 484 drug items, procurement frequency consisted of 279 low-frequency, 196 medium-frequency, and 9 high-frequency items. The percentage of dead stock was 3.37%, while expired and damaged drugs accounted for 0.02%, meeting the standard of less than 1.
subject: Articles
  topic: section
subject: Drug management
  topic: keywords
subject: Planning achievement
  topic: keywords
subject: Procurement frequency
  topic: keywords
subject: Dead stock
  topic: keywords
subject: Expired drugs
  topic: keywords
creator: Noor Aisyah
creator: Nanda Oktaviani
creator: Abdul Mahmud Yumassik
creator: Amaliyah Wahyuni
creator: Roseyana Asmahanie
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 418
ending page: 426
doi: 10.36387/jifi.v8i2.2861

TINGKAT KEPUASAN PASIEN DAN FAKTOR-FAKTOR YANG MEMPENGARUHI TERHADAP LAYANAN ANTAR OBAT (YANTARO) DEPO FARMASI RAWAT JALAN DI RSUD H. BADARUDDIN KASIM TABALONG
type: item
description: The drug delivery service (YANTARO) is innovative pharmaceutical service at H. Badaruddin Kasim Regional Hospital, Tabalong, designed improve patient convenience, reduce queues, and accelerate patient access to medications. This study aims evaluate level of patient satisfaction and the factors that influence satisfaction with YANTARO service. The research employed a quantitative method with cross-sectional approach, involving 43 outpatient respondents who utilized the YANTARO service. Data were collected using a questionnaire based on the Servqual dimensions (tangibles, reliability, responsiveness, assurance, and empathy) and were analyzed descriptively. The validity and reliability tests indicated that the research instruments were valid (r-count > 0.361) and reliable (Cronbach’s Alpha 0.919 for service factors and 0.808 for patient satisfaction). The findings show the YANTARO drug delivery service at the Outpatient Pharmacy Depot of H. Badaruddin Kasim Hospital is effective in improving patient satisfaction. The overall level patient satisfaction was high, with ease of access being the highest-rated indicator, while medication information delivery still requires improvement. The factors that most influenced patient satisfaction were the condition of medication upon delivery and the attitude of staff during the delivery process. Overall, the YANTARO service successfully reduced queues, saved patients’ time, and provided convenience for outpatients in obtaining their medications.
subject: Articles
  topic: section
subject: Patient Satisfaction
  topic: keywords
subject: Pharmaceutical Services
  topic: keywords
subject: Drug Delivery Service
  topic: keywords
subject: Hospital Pharmacy
  topic: keywords
creator: Yoga Kusuma Wardhani
creator: Misgiati
creator: Mayang Aditya
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 391
ending page: 406
doi: 10.36387/jifi.v8i2.2850

PROFIL KANDUNGAN FENOLIK DAN EVALUASI PARAMETER NON-SPESIFIK EKSTRAK ETANOL RIMPANG JAHE MERAH (Zingiber officinale var. rubrum)
type: item
description: Jahe merah (Zingiber officinale var. rubrum) merupakan tanaman obat yang diketahui memiliki aktivitas antiinflamasi dan antioksidan. Penelitian ini bertujuan untuk menstandarisasi ekstrak etanol jahe merah melalui penentuan kandungan fenolik total dan parameter non-spesifik. Ekstraksi dilakukan dengan metode maserasi menggunakan etanol 75% selama 1x24 jam. Kandungan fenolik total dianalisis dengan menggunakan metode Follin-Ciocalteu dan hasilnya dinyatakan dalam satuan mg GAE. Parameter non-spesifik yang ditentukan meliputi kadar air, kadar abu, dan kadar sari larut etanol dengan metode gravimetri. Hasil analisis menunjukkan ekstrak etanol jahe merah memiliki kadar air sebesar 12,87%, kadar abu 7,45%, kadar sari larut etanol 6,23% dan kandungan fenolik total sebesar 136,7mg GAE/g ekstrak. Data ini memberikan dasar ilmiah untuk standarisasi ekstrak jahe merah sehingga dapat digunakan sebagai bahan baku produk farmasi dengan mutu yang terukur.
subject: Articles
  topic: section
subject: Moisture content
  topic: keywords
subject: kadar abu
  topic: keywords
subject: Standarisasi
  topic: keywords
subject: Jahe Merah
  topic: keywords
subject: sari larut etanol
  topic: keywords
subject: total fenolik
  topic: keywords
subject: Bahan alam
  topic: disciplines
creator: Trias Kania Sundari
creator: Moch. Saiful Bachri
creator: Laela Hayu Nurani
creator: Wahyu Widyaningsih
creator: Muhammad Ma'ruf
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 449
ending page: 460
doi: 10.36387/jifi.v8i2.2832

STUDI PENGGUNAAN ANTIBIOTIK PADA PASIEN ULKUS DIABETIKUM DI INSTALASI RAWAT INAP RS X SEMARANG DENGAN PENDEKATAN ATC/DDD DAN DU 90%
type: item
description: Ulkus diabetik merupakan infeksi berat dari komplikasi diabetes melitus yang memiliki risiko amputasi. Dalam penanganannya, antibiotik memegang peranan penting. Namun, apabila penggunaannya tidak sesuai indikasi atau dosis, hal ini dapat memicu peningkatan resistensi bakteri. Penelitian ini bertujuan memberikan gambaran mengenai pola pemakaian antibiotik pada pasien ulkus diabetik yang dirawat di Instalasi Rawat Inap RS X Semarang. Evaluasi dilakukan menggunakan pendekatan ATC/DDD serta DU 90%. Desain penelitian yang dipakai adalah studi observasional deskriptif dengan pengambilan data secara retrospektif. Data diambil dari pasien rawat inap selama periode Januari sampai Desember 2024 yang memenuhi kriteria inklusi maupun eksklusi. Hasil menunjukkan ceftriaxone merupakan antibiotik dengan tingkat penggunaan tertinggi, yakni 9,81 DDD per 100 hari rawat inap. Sementara itu, berdasarkan analisis DU 90%, antibiotik yang paling dominan digunakan berada dalam kelompok ceftriaxone, metronidazole, levofloxacin, ampicillin-sulbactam, dan meropenem.
subject: Articles
  topic: section
subject: Diabetic ulcer, Antibiotics, ATC/DDD, DU 90%
  topic: keywords
subject: Farmasi Klinis
  topic: disciplines
creator: Anisa Devi Kharisma Wibowo
creator: Yesi Crystiana Putri
creator: Danik Sulistyoningsih
creator: Fransisca Gloria
creator: Anak Agung Pradnya Paramitha Vidiani
creator: Anisa Nova Puspitaningrum
creator: Muhammad Reza Mahendra
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 381
ending page: 390
doi: 10.36387/jifi.v8i2.2829

EVALUASI AKTIVITAS ANTIBAKTERI SABUN VCO pH NETRAL TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli
type: item
description: Liquid bath soap is widely used as an antiseptic in daily activities, but its generally high pH can erode the skin’s protective barrier and reduce comfort. Saponification is the reaction between a strong base and fatty acids. Virgin Coconut Oil (VCO), which contains lauric acid, is known for its antibacterial properties. This study aimed to determine the characteristics of VCO-based liquid soap and compare its antibacterial effectiveness against two structurally different bacteria, Staphylococcus aureus and Escherichia coli. The research employed a post-test only experimental design with descriptive-quantitative data collection. The stages included organoleptic evaluation, pH measurement, viscosity, specific gravity, and foam height testing. Only samples that fulfilled standard soap characteristics were further tested using the Kirby-Bauer diffusion method. Results showed that the soap met physical requirements, exhibiting a liquid texture, gray color, vanilla aroma, pH 7.08, viscosity of 1370 mPas, specific gravity of 1.01 g/mL, and foam height of 2 cm. The neutral-pH VCO soap demonstrated antibacterial activity against both S. aureus and E. coli. Statistical analysis using the Mann-Whitney test yielded an Asymp.Sig value of 0.083, indicating no significant difference between the antibacterial effects, suggesting broad antibacterial coverage. These findings support the potential of VCO soap for daily hygiene.
subject: Articles
  topic: section
subject: Antibacterial activity
  topic: keywords
subject: Escherichia coli
  topic: keywords
subject: Liquid soap
  topic: keywords
subject: Staphyloccus aureus
  topic: keywords
subject: virgin coconut oil
  topic: keywords
subject: Farmasi
  topic: disciplines
creator: Naomi Dwi Cahyanti
creator: Whisnu Trie Seno Ajie
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 369
ending page: 380
doi: 10.36387/jifi.v8i2.2827

FORMULASI SEDIAAN KRIM KOMBINASI EKSTRAK ETANOL MESOKARP SEMANGKA (Citrullus lanatus (Thunb.) dan BUAH TOMAT (Solanum lycopersicum L.) SEBAGAI TABIR SURYA
type: item
description: Ekstrak etanol mesokarp semangka (Citrullus lanatus (Thunb) dan buah tomat (Solanum lycopersicum L.) mengandung Flavonoid berperan sebagai tabir surya kimia yang menyerap sinar UV. Tabir surya melindungi kulit dari paparan sinar matahari dengan meyerap dan memantulkan sinar matahari. Tujuan diformulasikan sediaan krim kombinasi ekstrak etanol mesokarp semangka dan buah tomat untuk mengetahui efektifitas tabir surya berdasarkan nilai SPF, %TE dan %TP. Sediaan krim tabir surya kombinasi ekstrak etanol mesokarp semangka dan buah tomat diformulasikan dalam F1 (0:0); F2 (10:0); F3 (0:10); F4 (5:5); F5 (6:4); F6 (4:6) dan F7 (kontrol positif). Uji efektifitas tabir surya menggunakan Spektrofotometer UV-Vis pada panjang gelombang 290-375 nm, serta evaluasi sediaan mutu. Evaluasi sediaan krim menghasilkan sediaan homogen, pH berkisar 5,1±0,09–7,5±0,12, daya sebar berkisar 5,1±0.12–6,9±1,31 dan viskositas berkisar 9.333±471,40– 46.666 ± 942,81 cps serta didapat tipe emulsi m/a. Nilai SPF tertinggi didapat pada 1000 ppm yaitu F1 (0,35); F2 (3,56); F3 (3,04); F4 (3,04); F5 (4,59); F6 (3,13) dan F7 (9,57) nilai %TE dan %TP yang baik diperoleh konsentrasi 1000 ppm pada F5 yaitu %TE (0,312) dan F6 untuk %TP (0,215) masuk kategori sunblock. Sediaan krim memenuhi persyaratan evaluasi sediaan mutu, nilai SPF tertinggi terdapat pada F5, nilai %TE dan %TP efektif sebagai tabir surya.
subject: Articles
  topic: section
subject: krim
  topic: keywords
subject: sunscreen
  topic: keywords
subject: SPF
  topic: keywords
subject: %TE
  topic: keywords
subject: %TP
  topic: keywords
subject:
  topic: disciplines
  value: "Disciplines are fields of study or branches of knowledge that are usually categorized and organized by university faculties or learned societies, such as sciences, humanities, social sciences, arts, and professional studies."
creator: Reski Mulia
creator: Agis Alis Sandra
creator: Mochamad Fajar Deliaz
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 342
ending page: 358
doi: 10.36387/jifi.v8i2.2800

AKTIVITAS SITOTOKSIK EKSTRAK ETIL ASETAT DAUN AKAR KAIK-KAIK (Uncaria cordata (Lour.) Merr) PADA SEL KANKER SERVIKS HeLa
type: item
description: Cervical cancer is one of the leading causes of death in women worldwide and is a highly prevalent disease in developing countries. Efforts to prevent and treat cervical cancer continue to be developed, one of which is through the use of natural ingredients that have anticancer activity. This study aims to determine the cytotoxic activity of ethyl acetate extracts of Kaik-Kaik root leaves (Uncaria cordata (Lour.) Merr) against HeLa cervical cancer cells in vitro. Kaik-Kaik root leaves were extracted using a stepwise maceration method with n-hexane, ethyl acetate, and methanol solvents. The ethyl acetate extract was then tested for its cytotoxic activity using the MTT assay at various concentrations. Phytochemical screening results showed the presence of secondary metabolites such as flavonoids, tannins, saponins, and terpenoids that play a role in biological activity. Cytotoxicity test results showed that the ethyl acetate extract had very strong potential with an IC₅₀ value of 0.524 μg/mL, which is classified as highly toxic to cancer cells. These findings indicate that Uncaria cordata has the potential to be developed as a herbal-based anticancer agent. This study is expected to contribute to the development of safer, more effective, and more affordable alternative therapies for cervical cancer patients.
subject: Articles
  topic: section
subject: Cytotoxic
  topic: keywords
subject: Ethyl acetate extract
  topic: keywords
subject: HeLa cells
  topic: keywords
subject: MTT assay
  topic: keywords
subject: Uncaria cordata
  topic: keywords
subject: Biology Pharmacy
  topic: disciplines
creator: Noveri Rahmawati
creator: Nur Annisya Ulfa
creator: Izza Aulia Rizqika Nasution
creator: Nurdina Putri
rights: Copyright (c) 2026 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 31
ending page: 40
doi: 10.36387/bv4qqc35

MOM IS HERO: PRENATAL-POSTNATAL CALENDAR SEBAGAI UPAYA PENCEGAHAN STUNTING DENGAN PENDEKATAN THEORY OF PLANNED BEHAVIOR
type: item
description: Stunting is a problem that has become a national concern in Indonesia. stunting can not only reduce the quality of human resource (HR) in Indonesia but also can threaten the nation’s competitiveness (Simamora, 2021). Based on Basic ealth Research Data the national stunting prevalence rate in 2021 is 244% (Kemenkes, 2022). The aim of tis research is to describe the behavior of pregnant women and breastfeeding mothers towards “Mom is Hero” calendar. The research method uses a pre-experimental method with a One Group pretest-posttest design. Then the data was analyzed using the Pair t-test. In this study the t significance result for the variables of attitude, subjective norms and preceived behavioral control were 0.000.
subject: Articles
  topic: section
subject: stunting
  topic: keywords
subject: educational media
  topic: keywords
subject: calendar
  topic: keywords
subject: Bachelor of Pharmacy
  topic: disciplines
subject: Faculty of Health
  topic: disciplines
subject: Universitas Sari Mulia
  topic: disciplines
creator: Bella Safitri
creator: Regina Oktavia
creator: Khairunnisa Khairunnisa
creator: Devi Sarah
creator: Noval
creator: Melviani Melviani
rights: Copyright (c) 2025 Jurnal Insan Farmasi Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-12-31
publication date: 2025-12-31
starting page: 359
ending page: 368
doi: 10.36387/jifi.v8i2.2816