PENGARUH METODE EKSTRAKSI MASERASI DAN SOKLETASI TERHADAP STANDARDISASI PARAMETER SPESIFIK DAN NON SPESIFIK EKSTRAK ETANOL BIJI PEPAYA (Carica papaya L.)
DOI:
https://doi.org/10.36387/jifi.v6i1.1387Keywords:
Papaya seed, Carica papaya, Maceration, Soxhletation, Non specific parameters, Specific parametersAbstract
Papaya plant (Carica papaya L.) is a plant of Caricaceae family. Papaya has many health benefits, such as papaya seeds (Carica papaya L.) which can be used as medicine. This research is purely experimental with a research design to determine effect of maceration and soxhletation extraction methods on the standardization of specific and non-specific parameters of papaya seeds (Carica papaya L.). The result show  extraction method did not affect the standardization of specific parameters (total phenolic content) which showed no significant difference to the total phenolic content (standard gallic acid) as seen from the results of the analysis p sig 0.184 (p>0.05). The extraction method showed that there was a significant difference to the water content with a p sig of 0.046 (p <0.05). The total ash content and specific gravity showed a significant difference to the extraction method with a p sig 0.000 (p <0.05). The conclusion of this study is that there is an influence of maceration and soxhletation extraction methods on non-specific parameters, moisture content, total ash content and specific gravity. Meanwhile, there was no effect of soxhletation and maceration extraction methods on specific parameters total phenolic content.
References
Oktofani LA, Suwandi JF, Kedokteran F, Lampung U, Parasitologi B, Kedokteran F, et al. Potensi Tanaman Pepaya ( Carica papaya ) sebagai Antihelmintik. J Major. 2019;8(1):246–50.
Rauf SH, Isa I, Musa WJ a. Ekstraksi Senyawa Fenolik Dari Biji Pepaya (Carica papaya Linn.). Normalita. 2021;9(3):553–61.
Khasanah R, Wahidah BF, Hayati N, ... Etnobotani tanaman pepaya di daerah Moga Kecamatan Moga Kabupaten Pemalang. Pros Semin …. 2020;(September):363–71.
Altahira S. Utilization of Local Papaya In Second-trimester Pregnant Women Toward The Breast Milk (ASI) Quantity In Kontunaga District, Muna Southeast Sulawesi 2019. Keperawatan Indones dan Kebidanan. 2019;7642(2503–1856):184–9.
Damayanti KW, Purnama LS, Setyawati Trisna E. Aktivitas Antibakteri Ekstrak Etanolik Biji Pepaya (Carica papaya L .) : Narative Review (Antibacterial Activity Of Ethanolic Extract Of Carica Papaya (Carica papaya L .) Seed : Narative Review). J Curr Pharm Sci. 2021;4(2):355–9.
Emelda, Safitri EA, Fatmawati A. Aktivitas Inhibisi Ekstrak Etanolik Ulva lactuca terhadap Bakteri Staphylococcus aureus An Activity of Ethanolic Extract of Ulva lactuca in Inhibiting Staphylococcus aureus. 2021;7(1):43–7.
Heinrich M, Barnes J, Gibbons S, Williamso., M. E. Fundamental of Pharmacognocy and Phytotherapy. Philadelpia, Elsevier. 2004;
Departemen Kesehatan RI. Farmakope Herbal Indonesia. Jakarta: Departemen Kesehatan Reppublik Indonesia; 2008.
Departemen Kesehatan RI. Parameter Standar Umum Ekstrak Tumbuhan. In Jakarta: Departemen Kesehatan Republik Indonesia; 2000. p. Cetakan Pertama 3-11, 17-19.
Torar GMJ, Lolo WA, Citraningtyas G. Uji Aktivitas Antibakteri Ekstrak Etanol Biji Pepaya (Carica papaya L.) Terhadap Bakteri Pseudomonas aeruginosa dan Staphylococus aureus. PHARMACON [Internet]. 2017 May 2 [cited 2021 Mar 15];6(2). Available from: https://ejournal.unsrat.ac.id/index.php/pharmacon/article/view/15833
Sa’adah H, Nurhasnawati H, Permatasari V. Pengaruh Metode Ekstraksi Terhadap Kadar Flavonoid Ekstrak Etanol Umbi Bawang Dayak (Eleutherine palmifolia(L.)Merr) dengan Metode Spektrofotometri. J Borneo J Pharmascientech. 2017;01(01):1–9.
Kementrian Kesehatan Republik Indonesia. Farmakope Hebal Indonesia. II. Jakarta: Kementrian Kesehatan Republik Indonesia; 2017. 1–539 p.
Dewantara LAR, Ananto AD, Andayani Y. Penetapan Kadar Fenolik Total Ekstrak Kacang Panjang (Vigna unguiculata) dengan Metode Spektrofotometri UV-Visible. Lumbung Farm J Ilmu Kefarmasian. 2021;2(1):102.
Wijaya H, Novitasari, Jubaidah S. Perbandingan Metode Ekstraksi Terhadap Rendemen Ekstrak Daun Rambui Laut (Sonneratia caseolaris L. Engl). J Ilm Manuntung. 2018;4(1):79–83.
Nurhasnawati H, Sukarmi S, Handayani F. Perbandingan Metode Ekstraksi Maserasi dan Sokletasi terhadap Aktivitas Antioksidan Ekstrak Etanol daun Jambu Bol (Syzygium malaccense L.). J Ilm Manuntung. 2017;3(1):91.
Aulia Rahman IT. Perbedaan Total Flavonoid Antara Metode Maserasi Dengan Sokletasi Pada Ekstrak Daun Ramania (Bouea macrophylla Griff). J Kedokt Gigi. 2017;1(1).
Betan PT. Uji Aktivitas Krim Ekstrak Biji Buah Pepaya (Carica papaya L) Terhadap Aktivitas Bakteri Staphylococcus aureus. In: Skripsi. Tulungagung; 2019.
Ramayani SL, Nugraheni DH, Wicaksono ARE. Pengaruh Metode Ekstraksi Terhadap Kadar Total Fenolik dan Kadar Total Flavonoid Daun Talas (Colocasia esculenta L.). J Farm (Journal Pharmacy). 2021;10(1):11–6.
Anshari MA. Penentuan Senyawa Kafein Dan Total Fenol Pada Ekstraksi Ampas Kopi Robusta (Coffea Canaphora) Dengan Metode Ekstraksi Microwave Assisted, Sokletasi, dan Maserasi Serta Uji Aktivitas Antibakteri Staphylococcus aureus. Univ Islam Indones. 2018;
Syafrida M, Darmanti S, Izzati M. Pengaruh Suhu Pengeringan Terhadap Kadar Air, Kadar Flavonoid dan Aktivitas Antioksidan Daun dan Umbi Rumput Teki (Cyperus rotundus L.). Bioma Berk Ilm Biol. 2018;20(1):44.
Mondy NI, Geddeâ€Dahl SB, Mobley EO. Relationship of Specific Gravity to the Enzymatic Activity and Phenolic Content of Potatoes. J Food Sci. 1966;31(2):157–60.
Suhendy H, Wulan LN, Laili N, Keahlian DHK, Farmasi B. Pengaruh Bobot Jenis Terhadap Kandungan Total Flavonoid dan Fenol Ekstrak Etil Asetat Umbi Ubi Jalar Ungu-Ungu (Ipomoea batatas L.). Pengaruh Bobot Jenis … J Pharmacopolium. 2022;5(1):18–24.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Jurnal Insan Farmasi Indonesia
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
