UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BENALU BATU (Begonia sp) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli
DOI:
https://doi.org/10.36387/jifi.v6i2.1578Keywords:
Benalu batu leaf ekstract, Staphylococcus aureus, Escherichia coli, InhibitionAbstract
Empirically, begonia leaves are used as a treatment for cancer and ulcers. contains chemical compounds of flavonoids, alkaloids, saponins, tannins and steroids. This study aims to determine the antibacterial activity of ethanol extract of begonia and its effective concentration against Escherichia coli and Staphylococcus aureus bacteria. Extraction with 96% ethanol extract using the maceration method. Phytochemical screening test, antibacterial test using various concentrations of 30%, 50%, 100%, positive control (ciprofloxacin) and negative control (aquadest steril) using the disk diffusion method. The results of the phytochemical screening of begonia extract contain alkaloids, flavonoids and tannins. The results of the antibacterial activity test for Staphylococcus aureus were obtained with an inhibitory zone concentration of 30%, namely 3.75 mm, 50%, namely 4.37 mm, and 100%, namely 4.87 mm. Meanwhile, Escherichia coli bacteria obtained a concentration of 30%, namely 4.37mm, 50%, namely 4.62 mm, and 100% is nm 4.75mm. The diameter of the inhibition zone for the positive control of ciprofloxacin against Staphylococcus aureus bacteria was 40.31mm and Escherichia coli was 44.12mm. The ethanol extract of begonia leaves can inhibit the growth of Staphylococcus aureus bacteria at a concentration of 100% is 4.87mm and Escherichia coli bacteria at a concentration of 100% is 4.75mm
References
Hannif, Mulyani, S. & Kuschitawaty. Faktor Risiko Diare Akut Pada Balita. J. Ber. Kedokt. Masy. 22, 10–17 (2011).
Anonim. Riset Kesehatan Dasar. (2013).
Oktasila, D., Nurhamidah & Handayani, D. Uji Aktivitas Antibakteri Daun Jeruk Kalamansi (Citrofortunella Microcarpa) Terhadap Bakteri Staphylococcus Aureus Dan Escherichia Coli. J. Pendidik. Dan Ilmu Kim. 3, 158–169 (2019).
Ritna, A., Anam, S. & Khumaidi, A. Identifikasi Senyawa Flavonoid Pada Fraksi Etil Asetat Benalu Batu ( Begonia Sp .) Asal Kabupaten Morowali Utara Identification Of Flavonoid Compounds In Ethyl Acetate Fraction Of Benalu Batu ( Begonia Sp .) Originated From North. 2, 83–89 (2016).
Sari, C. M. A., Andriani, D. & Wahyudi, D. Optimasi Kombinasi Hpmc Dan Carbopol Dalam Formula Sediaan Gel Hand Sanitizer Ekstrak Etanol Biji Pepaya (Carica Papaya L.) Serta Uji Aktivitas Antibakteri Terhadap Escherichia Coli. J. Insa. Farm. Indones. 3, 241–252 (2020).
Mahdi, N., Putra, F. & Manurung, N. Formulasi Dan Uji Aktivitas Sabun Cair Antiseptik Dari Ekstrak Kulit Buah Kapul (Baccaurea Macrocarpa). J. Ilm. Ibnu Sina 7, 10–18 (2022).
Mahdi, N. & Setiawan, D. Formulasi Gel Hand Sanitizer Dari Ekstrak Rimpang Kumala Tawar (Costus Speciosus) Sebagai Antiseptik. J. Curr. Pharm. Sci. 4, 321–327 (2021).
Setiawan, D., Mahdi, N. & Praristiya, M. R. S. Formulasi Sediaan Gel Peel-Off Ekstrak Buah Limpasu (Baccaurea Lanceolate (Miq) Mull.Arg.) Sebagai Antibakteri. J. Ilm. Ibnu Sina 6, 361–367 (2021).
Wahid, A. R. & Ittiqo, D. H. Daya Hambat Bakteri Staphylococcus Aureus Ekstrak Daun Gaharu (Aquilaria Malea L.) Sebagai Antibakteri. J. Insa. Farm. Indones. 2, 34–43 (2019).
Suciari, L. K., Mastra, N., Dewi, C. & Hs, W. Perbedaanzona Hambat Pertumbuhan S Taphylococcus Aureus Pada Berbagai Konsentrasi Rebusan Daun Salam ( Syzygium Polyanthum ) Secara In Vitro. 5, 92–100 (2017).
Nurbaety, B., Safwan & Haeroni, A. S. Uji Daya Hambat Ekstrak Daun Cengkeh ( Syzygium Aromaticum ) Terhadap Bakteri Escherichia Coli Dengan Menggunakan Metode Sumuran. J. Insa. Farm. Indones. 1, 274–281 (2018).
Suryani, N., Anggia, V. & Fachrunnisa, N. Uji Aktivitas Antibakteri Gel Ekstrak Etanol Daun Angsana (Pterocarpus Indicus Willd.) Terhadap Bakteri Staphylococcus Aureus. J. Insa. Farm. Indones. 3, 124–131 (2020).
Rijayanti, R. P. Uji Aktivitas Antibakteri Ekstrak Etanol Daun Mangga Bacang. (2014).
Azzahra, F. & Madhani, V. Aktivitas Antibakteri Ekstrak Etanol Daun Alpukat (Persea Americana Mill.) Terhadap Bakteri Staphylococcus Epidermidis. J. Ilm. Medicam. 4, (2021).
Napanggala, A. & Apriliana, E. Effect O F Jatropha’s (Jatropha Curcas L.) Sap Topically In The Level Of Cuts Recovery On White Rats Sprague Dawley Strain . Pengaruh Pemberian Getah Tanaman Jarak Pagar ( Jatropha Curcas L . ) Secara Topikal Terhadap Tingkat Kesembuhan Luka Iris Pada Tik. 26–35 (2014).
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