FORMULASI DAN UJI SIFAT FISIK SEDIAAN KRIM DENGAN VARIASI KONSENTRASI EKSTRAK ETANOL DAUN KELAPA SAWIT (Elaeis guineensis Jack)
DOI:
https://doi.org/10.36387/jifi.v7i2.2073Keywords:
palm leaves, cream, physical testAbstract
Elaeis guineensis Jack. leaves contain flavonoid compounds which act as antioxidants to protect the body from bad influences that can cause skin damage by free radicals. One of the technological developments to treat that can be assisted by cream preparations. Cream has various advantages, namely that it is easy to spread evenly, easy to clean or wash, practical and works on local tissue, not sticky, especially in o/w creams. The aim of this research was to determine the effect of variations in the concentration of palm oil leaf ethanol extract on the physical properties and antioxidant potential of oil palm leaf ethanol extract cream. Oil palm leaves were extracted using the maceration method using 96% ethanol solvent to produce a thick extract. Palm oil leaf ethanol extract is made in cream dosage form with varying concentrations of palm oil leaf ethanol extract, FI (0.5%), FII (1%), and FIII (1.5%). The cream preparations were tested for physical properties including organoleptic tests, homogeneity, pH, viscosity, stickiness and spreadability. Based on the test results, all cream formulas meet the test requirements for homogeneity, pH, viscosity, adhesion and spreadability according to the requirements for cream preparations for use on the skin.
References
Haerani, A., Chaerunisa, A. Y., & Subarnas, A. (2018). Artikel Tinjauan: Antioksidan Untuk Kulit. Farmaka, 16(2), 135–151
Dipahayu, D., Soeratri, W., & Agil, M. (2014). Formulasi Krim Antioksidan Ekstrak Etanol Daun Ubi Jalar Ungu ( Ipomoea batatas ( L .) Lamk ) Sebagai Anti Aging. Pharm Sci Res, 1(3), 166–179.
Sari, A. N. (2015). Antioksidan alternatif untuk menangkal bahaya radikal bebas pada kulit. Elkawnie: Journal of Islamic Science and Technology, 1(1), 63–68
Sharon, N., Anam, S., & Yuliet. (2013). Formulasi Krim Antioksidan Ekstrak Etanol Bawang Hutan (Eleutherine palmifolia L. Merr.). Online Jurnal of Natural Science, 2(3), 111–122. http://jurnal.untad.ac.id/jurnal/index.php/ejurnalfmipa/article/view/1872
Husni, P., Pratiwi, A. N., & Baitariza, A. (2019). Formulasi Krim Ekstrak Etanol Daun Kelor (Moringa oleifera Lamk). Jurnal Ilmiah Farmasi Farmasyifa, 2(2), 101–110. https://doi.org/10.29313/jiff.v2i2.4796
Puspitasari, A. D., Yuita, N. E., & Sumantri. (2017). Krim Antioksidan Ekstrak Etanol Daun Kopi Arabika ( Coffea Arabica ). Jurnal Ilmiah Teknosains, 3(2), 82–88.
Mukhlishah, N. R. I., Sugihartini, N., & Yuwono, T. (2016). Daya Iritasi dan Sifat Fisik Sediaan Salep Minyak Atsiri Bunga Cengkeh ( Syzigium aromaticum ) Pada Basis Hidrokarbon. Majalah Farmaseutik, 12(1), 372–376
Mulyani, S., H, B. A., Antara, N. S., & Putra, I. N. K. (2016). An Assessment of Antioxidant Characteristics from different ratios Of Turmeric and Tamarind ( Curcuma domestica Val . - Tamarindus indica L .) Leaves Extracts. Australian Journal Of Basic and Applied Sciences, 10(14), 347–353.
Hasniar, Yusriadi, & Khumaidi, A. (2015). Formulasi Krim Antioksidan Ekstrak Daun Kapas ( Gossypium sp .). Galenika Journal of Pharmacy, 1(1), 9–15.
Dina Mailana, Nuryanti, & Harwoko. (2016). Formulasi Sediaan Krim Antioksidan Ekstrak Etanolik Daun Alpukat (Persea americana Mill.). Acta Pharmaciae Indonesia, 4(2), 7–15
Azkiya, Z., Ariyani, H., & Nugraha, T. S. (2017). Evaluasi Sifat Fisik Krim Ekstrak Jahe Merah ( Zingiber Officinale Rosc . Var . Rubrum ) Sebagai Anti Nyeri. Journal of Current Pharmaceuitica Sciences, 1(1), 12–18.
Moilati, V. O., Yamlean, P. V. Y., & Rundengan, G. (2020). Formulasi Sediaan Krim Ekstrak Etanol Daun Bayam Merah (Amaranthus tricolor L.) Dan Uji Aktivitas Antioksidan Menggunakan Metode DPPH (1.1-diphenyl-2-picrylhydrazyl). PHARMACON, 9(3), 372–380.
Purwanti, N. U., Luliana, S., & Sari, N. (2018). Pengaruh Cara Pengeringan Simplisia Daun Pandan (Pandanus amaryllifolius) Terhadap Aktivitas Penangkal Radikal Bebas DPPH (2,2-difenil-1-pikrilhidrazil). Pharmacy Medical Journal, 1(2), 63–72.
Supomo, Warnida, H., & Sahid, B. M. (2019). Perbandingan Metode Ekstraksi Ekstrak Umbi Bawang Rambut (Allium chinense G.Don.) Menggunakan Pelarut Etanol 70% Terhadap Rendemen Dan Skrining Fitokimia. Jurnal Riset Kefarmasian Indonesia, 1(1), 30–40.
Susanty, & Bachmid, F. (2016). Perbandingan Metode Ekstraksi Maserasi dan Refluks terhadap Kadar Fenolik dari Ekstrak Tongkol Jagung (Zea mays L.). Konversi, 5(2), 87–93.
Saputra, A. N., & Yudhantara, S. M. (2019). Formulasi Krim Ekstrak Etanol Kulit Buah Manggis (Garcinia Mangostana Linn.) Sebagai Antioksidan Menggunakan Variasi Asam Stearat Dan Trietanolamin. Jurnal Farmasi & Sains Indonesia, 2(1), 11–20
Arbie, S., Sugihartini, N., & Wahyuningsih, I. (2020). Formulasi krim m/a dengan variasi konsentrasi ekstrak buah pepaya (Carica papaya L.) menggunakan emulgator asam stearat dan trietanolamin. Media Farmasi, XVI(1), 97–104.
Pogaga, E., Yamlean, P. V. Y., & Lebang, J. S. (2020). Formulasi Dan Uji Aktivitas Antioksidan Krim Ekstrak Etanol Daun Murbei ( Morus alba L .) Menggunakan Metode DPPH ( 1 , 1-Diphenyl-2-Picrylhydrazyl ). Pharmacon, 9(3), 349–356.
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