INTERAKSI EKSTRAK DAUN TEH HIJAU DAN BUAH CABE MERAH SEBAGAI ANTIHIPERGLIKEMIA ANAK
DOI:
https://doi.org/10.36387/jifi.v8i2.2863Keywords:
antihyperglycemia, green tea, red chili pepperAbstract
Diabetes mellitus is a condition in which blood sugar levels are very high and cannot be controlled for an extended period. Therefore, more effective alternative treatments are needed. One of the materials being studied is green tea leaves (Camellia sinensis L) and red chili peppers (Capsicum annuum L), both of which are known to have antihyperglycemic effects.
This study aims to determine the interaction between green tea leaf extract and red chili pepper extract in reducing blood glucose levels in mice with elevated blood sugar. A total of 25 mice were used and divided into 5 groups, each containing 5 mice. In the treatment, groups were given green tea leaf extract at a dose of 37.5 mg per 30 grams of body weight per day, red chili pepper extract at 12.5 mg per 30 grams of body weight per day, and metformin as a comparison at a dose of 169 mg per gram for 1 to 6 days or until blood glucose levels decreased. The parameter observed was the decrease in blood glucose levels. The results showed that the administration of green tea leaf extract and red chili pepper extract could significantly reduce blood glucose levels in mice.
References
1. Widiasari KR, Wijaya IMK, Suputra PA, 2021, Diabetes melitus tipe 2: Faktor risiko, diagnosis, dan tatalaksana, Ganesha Medicina Journal, 1(2), 114–120.
2. International Diabetes Federation.
3. Rismawan M, Handayani NMT, Rahayuni IGAR, 2023, Hubungan Kepatuhan Minum Obat Terhadap Kadar Gula Darah Sewaktu Pada Penderita Diabetes Mellitus Tipe 2. Jurnal Riset Media Keperawatan, 6(1):23–30. doi: 10.51851/jrmk.v6i1.373
4. Monika EE, Triyandi R, Rahayu ID, Kedokteran F, Lampung U, Kedokteran F, et al, 2024, Potensi Tanaman Obat pada Penyakit Diabetes Melitus Dan Komplikasinya, A Review Article, 14, 752–7.
5. Utomo AA, Andira Aulia R, Sayyidah Rahmah, Rizki Amalia, 2020, Faktor Risiko Diabetes Mellitus Tipe 2 A Systematic Review: AN-NUR Jurnal Kajian dan Pengembangan Kesehatan Masyarakat, 01(2):44–52.
6. Amandha RW, Putra AP, Raningsih NM, 2025, Uji Efektivitas Antidiabetes Ekstrak Daun Cabai (Capsicum Frutescens, L) Terhadap Tikus Putih Jantan Galur Wistar (Rattus norvegicus). Jurnal Kesehatan Sundaram, 2(2):142–8. doi: 10.52073/c7c1gf16
7. Sofia Z, Safitri CINH, Suci PR, Khoiriyah M, Sebrina NP, 2023, Nutraseutikal Jelly Drink Kombinasi Ekstrak Daun Kelor Dan Rimpang Temulawak Sebagai Anti Stunting Secara in Vivo. MEDFARM: Jurnal Farmasi dan Kesehatan, 12(2):105–19. doi: 10.48191/medfarm.v12i2.236
8. Arifianto N, Yuniar CR, H CIN, Yusrina A, 2025, Sedative Effectiveness of Essential Oils of Red Rose Flower ( Rosa Damascena ) and White Jasmine Flower ( Jasminum Sambac ) on Male Mice ( Musculus ) by Olfactory Aromatherapy. Jurnal of Innovative and Creativity, 5(2):5756–62.
9. Cikra Ikhda Nur Hamida Safitri MK, 2024, Aktivitas Antidiabetes Kombinasi Ekstrak Labu Kuning Dan Brotowali Secara In Vivo. Jurnal Media Laboratoria, (3):10–7.
10. Cikra Ikhda Nur Hamidah Safitri, Putri Ade Muhaimatus Solikhah, 2025, Kombinasi Ekstrak Secang (Cesalpinia Sappan L.) Dan Metformin Sebagai Anti Hiperglikemia Secara in Vivo. Jurnal Insan Farmasi Indonesia, 8(1):127–36, doi: 10.36387/jifi.v8i1.2506
11. Salsabilla SFN, Safitri CINH, 2025, Combination of Secang (Caesalpinia sappan L.) and Glibenclamide in Mice (Mus Muscullus) Hyperglycemia. MEDFARM: Jurnal Farmasi dan Kesehatan, 14(1):58–64, doi: 10.48191/medfarm.v14i1.562
12. Oktaviani SR, Nabilah UU, 2024, Aktivitas Anti Diabetes Teh Hijau Dan Teh Hitam ( In Vivo ) Anti diabetic Activity Of Green Tea And Black Tea ( In Vivo ). FoodTech : Jurnal Teknologi Pangan, 7(2):1–8.
13. Ikhda C, Hamidah NPA, 2020 Uji aktivitas antidiabetes kombinasi ekstrak herba sambiloto dan daun sirih hijau pada mencit. Seminar Nasional Pendidikan Biologi dan Saintek, 5:553–61.
14. Azizah FN, Fitriani A, 2022, Pengaruh Teh Hijau Terhadap Penurunan Kadar Glukosa Pada Wanita Penderita Diabetes Melitus 2. Jurnal Berkala Ilmiah Mahasiswa Ilmu Gizi Indonesai, 10(1):1–7.
15. Cicih A, Aligita W, Susilawati E, 2022, A Review : The pharmacokinetics and pharmacodynamics of metformin-herb interactions, Jurnal Ilmiah Farmasi, 18(1):13–25.
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