POTENTIAL OF LEMONGRASS LEAF EXTRACT (Cymbopogon citratus (DC.) Stapf) AS AN ANTIBACTERIAL INHIBITORY of Staphylococcus epidermidis
DOI:
https://doi.org/10.36387/jifi.v6i2.1601Keywords:
Antibacterial, Staphylococcus epidermidis, LemongrassAbstract
The concerns of antibiotic resistance have increased in recently years, this issue caused by long-term repeated use of antibiotics to treat bacterial illnesses. Lemongrass leaf (Cymbopogon citratus (DC.) Stapf) is one of the natural ingredients that can be used as an alternative antibacterial. The study objective is to determine the antibacterial activity of the ethanol extract of 70% cooking leaves against Staphylococcus epidermidis using diffusion methods. In addition, the Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) of extracts were determined using liquid dilution methods. The results of this study show that extract concentrations of 1,000,000 ppm have a barrier zone in the intermediate category when compared with the positive control, that is, clindamycin. Meanwhile, the MIC value obtained is 1250 ppm, while the MBC value is 5000 ppm. The results of statistical analysis showed that there were no significant differences in the inhibition zone diameter formed between the test concentrations.
References
Riani, Syafriani., "Hubungan Antara Motivasi dengan Kepatuhan Perawat Melaksanakan Hand Hygiene sebagai Tindakan Pencegahan Infeksi Nosokomial di Ruang Rawat Inap Rumah Sakit A". Jurnal Ners. vol 3, no 3, 49–59, 2019.
Sulistiyaningsih, W. M., " Review: resistensi antibiotik pada terapi pengobatan jerawat," Farmaka, vol. 16, hal. 213–221, 2018.
Centers for Disease Control and Prevention, “Antibiotic resistance threats in the United States, 2019,†Cdc. Published online 2019:148.
Liu C xiao. Overview on development of ASEAN traditional and herbal medicines. Chinese Herb Med. 2021;13(4):441-450.
Novitri SA, Kurniati NF. Combination effect of ethanol extract of pomegranate peel (Punica granatum L.) and lemongrass stalk (Cymbopogon citratus) against Staphylococcus aureus ATCC 6538,†vol. 39, no. SeSICNiMPH, hal. 20–25, 2021.
Ajijolakewu K, Kazeem MO, Ahmed RN, et al. Antibacterial Efficacies of Extracts of Lemon Grass (Cymbopogon citratus) on Some Clinical Microbial Isolates. Fountain J Nat Appl Sci. 2021;10(1):17-25.
Eby Juliana Sabrima1, Riona Sanjaya, Surmiasih YDS. Biomedical Journal of Indonesia. 2020;6(3):357-363.
Septianingrum NMAN, Hapsari WS. Syariffudin A. Identifikasi Kandungan Fitokimia Ekstrak Okra Merah (Abelmoschus Esculentus) dan Uji Aktivitas Antibiotik Terhadap J Insa Farm Indones. 2018;1(2):170-177.
Wahid AR, Ittiqo DH. Daya Hambat Bakteri Staphylococcus Aureus Ekstrak Daun Gaharu (Aquilaria malea L.) Sebagai Antibakteri. J Insa Farm Indones. 2019;2(1):34-43.
Kumalasari E, aina aina, ayu checaria noverda, aisyah noor. Uji Aktivitas Antibakteri Ekstrak Etanol Daun Bawang Dayak (Eleutherine palmifolia (L.) Merr) Terhadap Pertumbuhan Propionibacterium acne. J Insa Farm Indones. 2020;3(2):261-270.
Azzahra F, Padmasari D, Adhiarta K, Farmasi A, Yogyakarta I. Uji Aktivitas Antibakteri Dari Ekstrak Etanol Daun Kembang Sepatu (Hibiscus rosa sinensis L.) Terhadap Bakteri Staphylococcus epidermidis DAN Streptococcus mutans. J Insa Farm Indones. 2018;1(2):243-250.
Erlyn P. Efektivitas Antibakteri Fraksi Aktif Serai (Cymbopogon citratus) terhadap Bakteri Streptococcus mutans. Syifa’ Med J Kedokt dan Kesehat. 2016;6(2):111. doi:10.32502/sm.v6i2.1387
Noer S, Studi Pendidikan Biologi Fakultas Teknik P, dan Ilmu Pengetahuan Alam M. Uji Kualitatif Fitokimia Daun Ruta Angustifolia Rosa Dewi Pratiwi. Fakt Exacta. 2016;9(3):200-206.
Rahayu W. Penentuan Konsentrasi Hambat Minimum ( KHM ) Ekstrak Buah Melur ( Brucea javanica [ L .] Merr ) Terhadap Bakteri Escherichia coli Dan Staphylococcus aureus. Repos Univ Negeri Padang. Published online 2013:16-20.
CLSI, CLSI M100 Performance Standards for Antimicrobial Susceptibility Testing, 30th Edition, vol. 40, no. 1. 2020.
Hoseinzadeh E, Makhdoumi P, Taha P, et al. A review of available techniques for determination of nano-antimicrobials activity. Toxin Rev. 2017;36(1):18-32.
Lolongan RA, Waworuntu O, Mintjelungan CN. Uji konsentrasi hambat minimum (KHM) ekstrak daun pacar air (Impatiens balsamina L.) terhadap pertumbuhan Streptococcus mutans. e-GIGI. 2016;4(2).
Farmakope Herbal, “Herbal Indonesia Herbal,†hal. 307–310, 2017.
Ahsan, M.. (2018). Uji Daya Hambat Lotion Ekstrak Pelepah Sereh (Cymbopogon citratus) Terhadap Pertumbuhan Staphylococcus aureus. Jurnal Kesehatan Yamasi Makassar, 2(1), 1–9.
Umar M, Mohammed I, Oko J, Tafinta I, Aliko A, Jobbi D. Phytochemical Analysis and Antimicrobial Effect of Lemon Grass (Cymbopogon citratus) Obtained From Zaria, Kaduna State, Nigeria. J Complement Altern Med Res. 2016;1(2):1-8.
Azzahra F, Madhani V. Aktivitas Antibakteri Ekstrak Etanol Daun Alpukat (Persea americana Mill.) Terhadap Bakteri Staphylococcus epidermidis. J Insa Farm Indones. 2021;4(2).
Hartanti AI, Dewa I, Mayun Permana G, Kadek GA, Puspawati D. Itepa: Jurnal Ilmu dan Teknologi Pangan, Pengaruh Konsentrasi Etanol Pada Metode Ultrasonikasi Terhadap Aktivitas Antioksidan Ekstrak Daun Gonda (Sphenoclea zeylanica) Effect Of Ethanol Concentration In Ultrasonication Method On Antioxidant Activity Of Go. Itepa (Jurnal Ilmu dan Teknol Pangan). 2021;10(2):163-171.
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