PEMANFAATAN TRIGGER TOOL DALAM MONITORING DAN DETEKSI ADVERSE DRUG REACTION PADA PASIEN RAWAT INAP GERIATRI DI RSI PKU MUHAMMADIYAH PEKAJANGAN PEKALONGAN
DOI:
https://doi.org/10.36387/jifi.v7i2.2133Kata Kunci:
adverse drug reactions, adverse drug events, global trigger tool, trigger toolAbstrak
Pentingnya pemantauan dan deteksi adverse drug reaction (ADR) pada pasien rawat inap geriatri tidak bisa diabaikan. Pasien geriatri rentan terhadap efek samping obat karena perubahan fisiologis terkait penuaan, peningkatan jumlah obat yang dikonsumsi, dan peningkatan sensitivitas efek obat. Tujuan penelitian untuk mendeteksi ADR dengan menggunakan trigger tools pada pasien rawat inap geriatri di RSI PKU Muhammadiyah Pekajangan Pekalongan dan mengetahui hubungan karakteristik pasien dengan kejadian ADR. Metode penelitian observasional dengan desain kohort retrospektif. Sampel seluruh pasien geriatri usia ≥ 60 tahun dan dirawat inap lebih dari 48 jam periode Juli - September 2023. Instrumen penelitian menggunakan trigger tools dari pedoman geriatri Belanda. Analisis Data dengan software Microsoft Excel 2016 dan SPSS 21.0. Hasil penelitian terdeteksi 393 kombinasi trigger drug pada 34,1% (n = 197/577) pasien. Trigger insufisiensi ginjal, hiperglikemi, hiponatremia, hipotensi/pusing, dan diare/muntah mencakup 86,5% (n = 340/393). Positive predictive value (PPV) keseluruhan dari triggers 49,4%, mayoritas ADR disebabkan angiotensin receptor blocker (ARB), diuretik loop, NSAID, diuretik hemat kalium, dan kortikosteroid, yang mencakup 69% dari semua obat yang menyebabkan ADR. Analisis hubungan menunjukkan faktor usia memberikan pengaruh terjadinya ADR. Kesimpulan menunjukkan nilai trigger drug sebagai tools untuk mendeteksi ADR pada pasien geriatri rawat inap di RSI PKU Muhammadiyah Pekajangan Pekalongan.
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