PENGARUH SUHU PENYEDUHAN TERHADAP EFEK DIURETIK TEH HIJAU PADA MENCIT JANTAN GALUR SWISS
DOI:
https://doi.org/10.36387/jifi.v5i2.1148Keywords:
Temperature, Brewing, Green tea, Diuretic effectAbstract
Tea (Camelia sinensis L.) is a beverage that is familiar to the community and is drunk by brewing it. Green tea contains chemicals such as polyphenols, tannins, steroids and flavonoids. This study aimed to determine the effect of temperature brewing of green tea in the diuretic effect of male swiss strain mice.
This research is an experimental study with 25 mice which were divided into five groups, group I (CMC Na 1%), Group II (Furosemide dose 5.2 mg/KgBB), Group III,IV and V (green tea brewed at 50oC,70oC dan 90oC ) with a brewing time of 5-15 minutes. Urine measurements were performed every 1 hour for 6 hours. Data analysis was carried out using the One-Way ANOVA test followed by the LSD test with a 95% confidence level.
The results showed that the diuretic effect at a brewing temperature of 50oC was not significantly different (p> 0.05) with the diuretic effect at 70oC but the average volume of urine at 50oC was greater than 70oC. Diuretic effect at temperature 90oC was significantly different (p<0.05) compared to 50oC and 70oC. The diuretic effect of green tea can be optimal, if the brewed at a temperature of 50oC and 70oC for 5-15 minutes.
References
WHO. 2018. Global Health Estimates 2016: Deaths by Cause, Age, Sex, by Country and by Region, 2000- 2016. Geneva: World Health Organization.
Snigdha M., Kumar S.S., Jaya Y. and Kasana B., 2013, Review Article a Review on “How Exactly Diuretic Drugs Are Working in Our Bodyâ€. Journal of Drug Delivery & Therapeutics. 3 (5): 115–120.
Nafrialdi, G., & Sulistia, G. (2011). Farmakologi dan Terapi Edisi 5 Cetakan Ulang Dengan Tambahan. Jakarta: Universitas Indonesia.
Redaksi Sehat Negeriku. 2011. Integrasi Pengobatan Tradisional dalam Sistem Kesehatan Nasional. https://sehatnegeriku.kemkes.go.id/baca/rilis-media/20111102/541807/integrasi-pengobatan-tradisional-dalam-sistem-kesehatan-nasional/. Diakses tanggal 28 Januari 2021.
Sariana. 2011. Uji Efek Analgetik Dari Infusa Daun Asam Jawa (Tamarindus indica Linn) Pada Mencit (Mus muskulus). Skripsi. Makassar : Universit.as Islam Negeri Alauddin
Winarti., L dan Wantiyah. 2011. Uji Efek Analgetik Ekstrak Rimpang Temu Kunci (Boesenbergia pandurata Roxb) Schlechter Pada Mencit Jantan Galur Swiss. Majalah Obat Tradisional. 16(1): 26-33.
Susilowati, Agustina. 2019. Diuretic Effect Of The Aqueous Extract Of Green Tea Leaves. Advances in Health Science Research. 15: 33-36.
Harwiningrum, Ragilia Puspita. 2020. Pengaruh Suhu dan Waktu Penyeduhan Terhadap Aktivitas Anti Oksidan Teh Hitam (Camellia sinensis) dengan Perekasi DPPH Metode Spektrofotometri UV-VIS. Skripsi. Surabaya: Universias Airlangga
Mutmainnah, Nurul., Sitti Chadijah, Muh.Qaddafi. 2018. Penentuan Suhu dan Waktu Optimum Penyeduhan Batang Teh Hijau (Camellia sinensis, L.) Terhadap Kandungan Antioksidan Kafein, Tanin dan Katekin. Lantanida Journal. 1(6):1-102
Marlyne, I,S., Citraningtyas, G., dan Lolo, W,A., 2012. Uji Efek Analgetik Ekstrak Etanol 70% Bunga Mawar (Rosa chinesis Jacq.) Pada Mencit Yang Diinduksi Asam Asetat. Skripsi. Depok: FMIPA Universitas Indonesia.
Herman, H., Azizah, R.N., dan Inaku, C., 2012. Uji Efek Diuretik Infus Biji Jagung (Zea mays L.), Rambut Jagung Dan Kombinasi Antar Keduanya Pada Kelinci Jantan (Oryctolagus cuniculus) Berdasarkan Parameter Frekuensi Urinasi Dan Volume Urin. As-Syifa. 04(01): 65-73.
Susilowati, Agustina. 2019. Diuretic Effect Of The Aqueous Extract Of Green Tea Leaves. Advances in Health Science Research. 15: 33-36.
Susilowati, Agustina dan Ramadhan N.K.K., 2021. Perbandingan Aktivitas Diuretik pada Berbagai Produk Seduhan Teh Hijau (Camellia sinensis, L.), Majalah Farmasetika. 6(1):71-79
Susilowati, Agustina dan Indratika, S.N., 2020, Comparative effectiveness of the ethanol extract and infusion of green tea leaves (Camellia Sinensis L.) as a diuretic in male swiss mice, Phamaciana, Vol.10 (2): 185-192
Putri, D. D. dan Ulfin, I. 2015. Pengaruh Suhu dan Waktu Ekstraksi terhadap Kadar Kafein dalam Teh Hitam. Jurnal Sains dan Seni ITS; 4; 2337- 3520.
Chadijah, Sitti., Musdalifah, Muhammad Q., Firnanelty., 2021, Optimalisasi Suhu Dan Waktu Penyeduhan Daun Teh Hijau (Camellia Sinensis L.) P+3 Terhadap Kandungan Antioksidan Kafein, Katekin Dan Tanin, Bencoolen Journal of Pharmacy, 1(1): 59-65
Jahangiri, Y., H. Ghahremani., J.A. Torghabeh., dan E.A. Salehi. 2011. Effect of temperature and slovent on the total phenolic compounds extraction from leaves of Ficus carica. Journal of Chemical and Pharmaceutical Research. 3(5):253-259.
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