EVALUASI PENGGUNAAN ANTIBIOTIK DENGAN METODE GYSSENS PADA PASIEN DEMAM TIFOID ANAK DI INSTALASI RAWAT INAP RSUP Dr. SITANALA TAHUN 2019-2021

Authors

  • Sefi Megawati Universitas Muhammadiyah A.R. Fachruddin
  • Nuraini Nuraini Universitas Muhammadiyah A.R. Fachruddin
  • Febby Carolina Universitas Muhammadiyah A.R. Fachruddin

DOI:

https://doi.org/10.36387/jifi.v6i3.1641

Keywords:

Antibiotics, Typhoid fever, Gyssens

Abstract

Typhoid fever is a disease caused by bacteria and its treatment requires antibiotics. Antibiotic-resistant bacteria can grow as a result of improper use of antibiotics. The purpose of this study was to determine the rational usage pattern and percentage of antibiotic drug use according to the Gyssens method. This non-experimental study employed retrospective data collecting from the medical records of children treated for typhoid fever at the Dr. Sitanala in 2019–2021 and used the Gyssens technique for analysis. According to the study's findings, 28 patients (46.67%) were classified as irrational, whereas 32 patients (53.33%) were considered rational (category 0). In this study, it can be concluded that the use of antibiotics used in typhoid fever patients, namely ceftriaxone (82,54%), cefotaxime (14.29%), and cefixime (3.17%) with the intravenous route of administration (96.83%) and orally (3.17%). Irrational use of antibiotics included Gyssens category V (antibiotics are not needed) (1.67%), category IVC (there are cheaper antibiotics) (11,86%), category IIIB (the duration of giving antibiotics are too short) (30,51%), category IIA (not the right doses) (20,34%), and category I (not on time to give antibiotics) (18.64%).

References

Kemenkes, “Keputusan Menteri Kesehatan Republik Indonesia Nomor 64/MENKES/SK/V/2006 Tentang Pedoman Pengendalian Demam Tifoid,†2006 Diakses: 7 Juli 2023.

N. H. Rampengan, “Antibiotik Terapi Demam Tifoid Tanpa Komplikasi pada Anak,†2013, Diakses: 7 Juli 2023. [Daring]. Tersedia pada: https://www.saripediatri.org/index.php/sari-pediatri/article/download/325/266.

Juwono R. dan Prayitno A., “Terapi Antibiotik,†Dalam: Farmasi Klinik, Ed Aslam: Elex Media Komputindo , hal: 321-323. Jakarta. 2003.

D. Astuti dan Y. Nurhayati, “Evaluasi Kualitatif Penggunaan Antibiotik Pada Pasien Anak Dengan Metode Gyssens Di Rsud Karawang,†2018, Diakses: 7 Juli 2023. [Daring]. Tersedia pada: http://journal.ubpkarawang.ac.id/index.php/Farmasi/article/view/620.

A. Saputra Yasir, Y. Merliyanti, J. Farmasi, U. Malahayati, B. Lampung, dan I. Korespondensi Penulis, “Evaluasi rasionalitas penggunaan antibiotik pada pasien demam tifoid anak dengan metode Gyssens,†2021.

H. A. Ajum, “Evaluasi Kerasionalan Penggunaan Antibiotika Pada Pasien Anak Dengan Demam Tifoid Berdasarkan Kriteria Gyssens Di Instalasi Rawat Inap RSUD Panembahan Senopati Bantul Yogyakarta Periode Januari-Desember 2013,†2015, Diakses: 7 Juli 2023.

Permenkes, “Peraturan Menteri Kesehatan Republik Indonesia Nomor 28 Tahun 2021 Tentang Pedoman Penggunaan Antibiotik,†2021.

World Health Organization. “Guideline for the Management of Typhoid Feverâ€. WHO, 2011.

Permenkes, “Peraturan Menteri Kesehatan Republik Indonesia Nomor 25 Tahun 2014,†2014. Diakses: 7 Juli 2023. [Daring]. Tersedia pada: https://peraturan.bpk.go.id/Home/Details/117562/permenkes-no-25-tahun-2014.

F. L. Mustofa, R. Rafie, dan G. Salsabilla, “Characteristics of Typhoid Fever Patients in Children and Adolescents at,†2020

S. Retno Karminingtyas, A. Taufikarani, dan G. Seralurin, “Evaluasi Dosis Antibiotik Pada Pasien Demam Tyfoid Anak di Instalasi Rwat Inap RSI Sultan Agung Semarang dan RSUD Tugurejo,†2018.

S. Sidabutar dan Hindra Irawan Satari, “Pilihan Terapi Empiris Demam Tifoid pada Anak: Kloramfenikol atau Seftriakson?,†2010, Diakses: 7 Juli 2023. [Daring]. Tersedia pada: https://saripediatri.org/index.php/sari-pediatri/article/view/611.

S. Patattan, “Evaluasi Penggunaan Antibiotika Pada Pasien Demam Tifoid Rawat Inap Rumah Sakit Stella Maris Makassar Pada Tahun 2016,†2017.

Gyssens, I.C., Audit for Monitoring the Quality of Antimicrobial Prescription, Dalam: Gould, I.M., Van der Meer, penyunting, Antibiotic Policies: Theory and Practice. Kluwer Academic Publishers, New York: 192-208, 2005.

Kemenkes, “Buku Pedoman Umum Penggunaan Antibiotik,†2013.

L. Suhartaty, L. Pratiwi, dan N. U. Purwanti, “Evaluasi Penggunaan Antibiotik Pada Pasien Pediatrik Rawat Inap Di Rsud Dr. Soedarso Pontianak,†2019.

E. Kartika Untari, A. Renata Agilina, dan R. Susanti, “Evaluation on Rationality of Hypertension Treatment in Puskesmas Siantan Hilir Pontianak on 2015 Article History,†Original Article Pharmaceutical Sciences and Research, vol. 5, no. 1, hlm. 32–39, 2018.

Kemenkes, “Modul Penggunaan Obat Rasional (Kemenkes, 2011),†2011.

P. Taher, P. Oktanauli, dan S. Riskia Anggraini, “rasionalitas penggunaan antibiotika pada pasien poli gigi salah satu rumah sakit pendidikan di jakarta,†2020.

DIH. “Drug Information Handbook. American Pharmacists Association,†23rd Edition, 2014.

Published

2024-02-01

How to Cite

1.
Megawati S, Nuraini N, Carolina F. EVALUASI PENGGUNAAN ANTIBIOTIK DENGAN METODE GYSSENS PADA PASIEN DEMAM TIFOID ANAK DI INSTALASI RAWAT INAP RSUP Dr. SITANALA TAHUN 2019-2021. JIFI [Internet]. 2024 Feb. 1 [cited 2024 Feb. 22];6(3):127-38. Available from: https://e-jurnal.stikes-isfi.ac.id/index.php/JIFI/article/view/1641