FORMULATION AND STABILITY TEST OF GEL MASK ETYL ASETATIC FRACTION OF BUTTERFLY PEA FLOWER(Clitoria ternatea L.) AS ANTIOXIDANTS
DOI:
https://doi.org/10.36387/jifi.v8i1.2423Keywords:
gel mask, ethyl acetate, Butterfly pea flowerAbstract
The ethyl acetate fraction of butterfly pea flower was found to have higher antioxidant activity than other fractions. This fraction can be utilized in making gel mask preparations, as an alternative to topical antioxidants. The purpose of this study was to formulate the ethyl acetate fraction in a gel mask preparation, and test the physical characteristics and stability of antioxidant activity before and after being stored for 3 months at room temperature. Extraction of telang flowers, using 70% ethanol, followed by fractionation with n-hexane, ethyl acetate and water. The results of the ethyl acetate fraction were tested for antioxidant activity, then formulated in a gel mask preparation. Evaluation of the physical characteristics of the preparation includes organoleptic test, homogeneity, pH, viscosity, adhesion, spreadability, and antioxidant activity test, before and after 3 months storage with DPPH. The results of the antioxidant activity test of the ethyl acetate fraction obtained a value of 25.14 µg/mL. The results of the physical characteristics of the gel have a pH 5.18 ± 0.035, viscosity 9541 ± 32.14 cps, adhesion 2.04 ± 0.015 seconds, spreadability 4.55 ± 0.015 cm. The antioxidant activity of the gel decreased after storage for 3 months.
References
1. Nurkhasanah MA, Si A, Mochammad S, Bachri S, Si M, Si DS, et al. Antioksidan dan Stres Oksidatif. 2023. 1–3 p.
2. Haryono IA, Noval N, Nugraha B. Formulasi Buah Tampoi (Baccaurea macrocarpa) dalam Sediaan Masker Gel sebagai Antiaging. J Surya Med. 2021;6(2):102–10.
3. Nusaibah N, Cempaka CI, Abrian S, Susanti O, Andayani TR. Karakteristik Face Scrub dari Sediaan Simplisia Rumput Laut Sargassum sp. Maj Farmasetika. 2023;9(1):76.
4. Gupta GK, Chahal J, Bhatia M. Clitoria ternatea (L.): Old and new aspects. J Pharm Res. 2015;3(January 2010):2610–4.
5. Putu N, Cipta A, Jelantik R, Cahyaningsih E. Antioxidant potential of telang flowers ( Clitoria ternatea L .) as an inhibitor of hyperpigmentation due to ultraviolet exposure Potensi antioksidan bunga telang ( Clitoria ternatea L .) sebagai penghambat hiperpigmentasi akibat paparan sinar ultraviolet. 2022;45–54.
6. Rajamanickam M, Kalaivanan P, Sivagnanam I. Evaluation of anti-oxidant and anti-diabetic activity of flower extract of Clitoria ternatea L. J Appl Pharm Sci. 2015;5(8):131–8.
7. Andriani D, Murtisiwi L. Uji Aktivitas Antioksidan Ekstrak Etanol 70 % Bunga Telang ( Clitoria ternatea L ) dari Daerah Sleman dengan Metode DPPH Antioxidant Activity Test of 70 % Ethanol Extract of Telang Flower ( Clitoria ternatea L ) from Sleman Area with DPPH Method. 2020;1(1):70–6.
8. Yumni Gharsina, Sumantri; Nuraini da Nafis I. Profil Antioksidan dan Kadar Flavonoid Total Fraksi... (Yumni dkk.). 2021;12–7.
9. Cahyaningsih E, Yuda PESK, Santoso P. SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BUNGA TELANG (Clitoria ternatea L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS. J Ilm Medicam. 2019;5(1):51–7.
10. Molyneux P. The Use of the Stable Free Radical Diphenylpicryl-hydrazyl (DPPH) for Estimating Antioxidant Activity. Songklanakarin J Sci Technol. 2004;26(December 2003):211–9.
11. Juliadi D, Juanita RA. FORMULASI DAN UJI MUTU FISIK MASKER GEL KOMBINASI EKSTRAK ETANOL HERBA PEGAGAN (Centella asiatica (L.) Urb.) DAN NIASINAMIDA DENGAN VARIASI KARBOMER. J Farmagazine. 2022;9(1):71.
12. Susiloningrum D, Erliani D, Sari M. UJI AKTIVITAS ANTIOKSIDAN DAN PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK TEMU MANGGA ( Curcuma mangga Valeton & Zijp ) DENGAN VARIASI KONSENTRASI PELARUT. 2021;5(2):117–27.
13. Rumpf J, Schulze M. International Journal of Biological Macromolecules Statistical evaluation of DPPH , ABTS , FRAP , and Folin-Ciocalteu assays to assess the antioxidant capacity of lignins. 2023;233(February).
14. Nahhas AF, Abdel-Malek ZA, Kohli I, Braunberger TL, Lim HW, Hamzavi IH. The potential role of antioxidants in mitigating skin hyperpigmentation resulting from ultraviolet and visible light-induced oxidative stress. Photodermatol Photoimmunol Photomed. 2019;35(6):420–8.
15. Rachmawati D, Stevani H, Santi E. UJI STABILITAS MUTU FISIK SEDIAAN MASKER GEL WAJAH DARI EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L.) DENGAN VARIASI KONSENTRASI CARBOPOL. Media Farm. 2018;14(1):77.
16. Alfaris SM, Dhahir RK, Al-Nima AM. Preparation, Evaluation of Propolis Extract Gel and exploring its Antioxidant, Antimicrobial Activity. Pharmacogn J. 2022;14(6):675–81.
17. Nurwaini S, Fatimah MN. Formulation And Characterization Of Gels Of Telang Flower Extract ( Clitoria Ternatea L ) With Variations Of Carbopol Concentration And Antioxidant Activity Test Using Dpph Methods. Pharmacon J Farm Indones. 2024;21(1):145–51.
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