FORMULASI OBAT KUMUR EKSTRAK DAUN BINAHONG DAN KAYU MANIS TERHADAP BAKTERI Streptococcus mutans
DOI:
https://doi.org/10.36387/jifi.v6i3.1781Keywords:
mouthwash, binahong leaves, cinnamon, Streptococcus mutansAbstract
Dental caries is a disease in the oral cavity, this disease can be prevented by using mouthwash. Plants that have antibacterial activities include binahong leaves and cinnamon . This study aims was to determine the quality and antibacterial activity of mouthwash that containing against Streptococcus mutans. Mouthwash preparations was carried out by various concentrations of binahong leaves and cinnamon extract. Preparation F0 is without extract, F1 (6%:3%), F2 (7%:3%), F3 (8%:3%). The organoleptic test results of the mouthwash was clear brown in color and had a distinctive aroma of binahong leaves and cinnamon. The pH test results were F0 6.529±0.16; F1 5.256±0.004; F2 5.333±0.002; and F3 5.373±0.003. The density measurements results were F0 1.0766±0.04852; F1 1.0309±0.00056; F2 1.0317±0.00032; and F3 1.0364±0.00325. The viscosity measurement results were F0 3.170±0.02; F1 3.203±0.02; F2 3.323±0.01; and F3 3.380±0.02. The antibacterial activity test result were F0 0.00 mm; F1 6.39±0.03 mm; F2 7.29±0.06 mm; F3 8.89±0.07 mm; negative control (distilled water) 0.00 mm; and positive control (chlorhexidine 0.2%) 21.35±0.10 mm. The preparation fulfilled the physical quality parameter requirements of mouthwash and has antibacterial activity against Streptococcus mutans.
References
Nurlila, R. U., Fua, J. La & Meliana. Pengaruh Pendidikan Kesehatan terhadap Pengetahuan tentang Kesehatan Gigi pada Siswa di SD Kartika XX-10 Kota Kendari tahun 2015. J. Al-Ta’dib 9, 94–119 (2016).
Avilés-Reyes, A. et al. Modification of Streptococcus mutans Cnm by PgfS contributes to adhesion, endothelial cell invasion, and virulence. J. Bacteriol. 196, 2789–2797 (2014).
Tim Riskesdas 2019. Laporan Nasional Riskesdas 2018. Lembaga Penerbit Balitbangkes at (2019).
Rahmadina, D. Efektivitas Berkumur dengan Larutan Garam 10% Terhadap Penurunan Skor Plak. J. Kesehat. gigi 2, 53–63 (2020).
Rimporok, S., Kepel, B. J. & Siagian, K. V. Uji Efektifitas Ekstrak Daun Binahong (Anredera Cordifolia Steenis) terhadap Pertumbuhan Streptococcus mutans secara In Vitro. Pharmacon J. Ilm. Farm. – Unsrat 4, 15–21 (2015).
Prasetyorini, Utami, N. F., Yulianita, Novitasari, N. & Fitriyani, W. Potensi Ekstrak Refluks Kulit Batang Kayu Manis (Cinnamomum burmannii) sebagai Antijamur Candida albicans dan Candida tropicalis. Fitofarmaka J. Ilm. Farm. 11, 164–178 (2021).
Intan, K., Diani, A. & Nurul, A. S. R. Aktivitas Antibakteri Kayu Manis (Cinnamomum burmanii) terhadap Pertumbuhan Staphylococcus aureus. J. Kesehat. PERINTIS (Perintis’s Heal. Journal) 8, 121–127 (2021).
Hasnaeni, Wisdawati & Usman, S. Pengaruh Metode Ekstraksi terhadap Rendemen dan Kadar Fenolik Ekstrak Tanaman Kayu Beta-Beta (Lunasia amara Blanco). J. Farm. Galen. (Galenika J. Pharmacy) 5, 166–174 (2019).
Depkes RI. Farmakope Indonesia Edisi IV. at (1995).
Nur Isnaeni, F., Nadya Risti, K., Mayawati, H., Khaulil Arsy, M. & Studi Ilmu Gizi, P. The Indonesian Journal of Health Promotion MPPKI Open Access. 1, 40–45 (2018).
Putri, M. R., Zulferiyenni, Susilawati & Murhadi. Pengaruh Penambahan Ekstrak Kayu Manis (Cinamommum burmanni) terhadap Sifat Kimia dan Mikrobiologi Minuman Probiotik Sari Jagung Manis (Zea Mays saccharata) Selama Penyimpanan. J. Agroindustri Berjelanjutan 2, 110–122 (2023).
Anastasia, A., Yuliet, Y. & Tandah, M. R. Formulasi Sediaan Mouthwash Pencegah Plak Gigi Ekstrak Biji Kakao (Theobroma cacao L) Dan Uji Efektivitas Pada Bakteri Streptococcus mutans. J. Farm. Galen. (Galenika J. Pharmacy) 3, 84–92 (2017).
Rachmawati, N., Ramayani, S. L. & Pradana, R. C. Formulasi dan Uji Stabilitas Obat Kumur Ekstrak Etanol 70% Biji Alpukat (Persea americana Mill.). J. Jamu Kusuma 2, 55–63 (2022).
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Jurnal Insan Farmasi Indonesia

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.