PENGARUH KONSENTRASI ASAM HIALURONAT TERHADAP STABILITAS FISIK SALEP KOMBINASI EKSTRAK IKAN GABUS

Authors

  • Lelek Kipli Universitas Tanjungpura
  • Mohamad Andrie Department Pharmacy, Faculty of Medicine, Tanjungpura University, Jl Prof. Dr. H Hadari Nawawi, Pontianak, West borneo, Indonesia
  • Wintari Taurina Universitas Tanjungpura

DOI:

https://doi.org/10.36387/jiis.v8i2.1452

Keywords:

Hyaluronic Acid, Humectant, Ointment, Physical Stability, Snakehead Fish

Abstract

The combination of snakehead fish ointment is expected to have synergistic properties in wound healing. Variations in natural ingredients added to the formula will affect the stability of the preparation during its shelf life. Hyaluronic acid, as a humectant agent, is used to maintain stability and improve physical properties by increasing the consistency of the preparation and reducing the risk of syneresis. The test method in this study was the stability test of the intermediate at 30°C ± 2°C/ RH 65 ± 5 % for six months. The Parameters measured were spreadability, adhesion, and pH. The observations showed that all formulas met the physical characteristics of the ointment until the 1st month. The 0.25% hyaluronic acid concentration was the most stable formula, which maintained the stability of spreadability and adhesion up to the 1st-month test point.

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Published

2023-10-31

How to Cite

Kipli, L., Andrie, M., & Taurina, W. (2023). PENGARUH KONSENTRASI ASAM HIALURONAT TERHADAP STABILITAS FISIK SALEP KOMBINASI EKSTRAK IKAN GABUS. Jurnal Ilmiah Ibnu Sina, 8(2), 265–275. https://doi.org/10.36387/jiis.v8i2.1452

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