EKSPLORASI HAMBATAN KEPATUHAN PENGOBATAN PASIEN DIABETES MELITUS DI PUSKESMAS: STUDI KUALITATIF
DOI:
https://doi.org/10.36387/jiis.v10i2.2789Keywords:
medication adherence, diabetes mellitus, primary health center, qualitative studyAbstract
Medication adherence is a crucial factor in the successful management of diabetes mellitus, yet many studies show that adherence remains low and is shaped by multidimensional influences. This study aimed to explore barriers to medication adherence among patients with diabetes mellitus in primary health centers (Puskesmas) using the WHO five-domain adherence framework. A qualitative descriptive-exploratory design was applied. Data were collected through in-depth interviews with ten patients undergoing routine treatment at Puskesmas in Banjarmasin City, recruited through purposive sampling. Thematic analysis was performed guided by the WHO adherence model. Five major themes emerged. Social and economic factors included limited transportation costs, distance to the health center, and lack of family support. Health system and provider factors involved brief consultations, insufficient patient education, and long queues. Condition-related factors comprised the absence of immediate symptoms, fatigue from chronic illness, comorbidities, and psychological distress. Therapy-related factors included complex regimens, side effects, and discontinuation of therapy without consultation. Patient-related factors were characterized by forgetfulness, reliance on alternative medicine, fluctuating motivation, and feelings of boredom. These findings highlight that adherence barriers are multidimensional and result from the interaction of individual, social, and system-level determinants. Addressing adherence requires holistic and continuous interventions at the primary care level, with emphasis on patient education, family involvement, and strengthening the role of healthcare providers.
References
alfian, R., Ariani, N., Nita, Y. & Athiyah, U. 2025a. Assessment to barriers of medication adherence among patients with Type 2 Diabetes Mellitus. Journal of Research in Pharmacy, 29, 918-927.
Alfian, R., Athiyah, U. & Nita, Y. 2021. Social media health interventions to improve diabetes mellitus patient outcome: a systematic review. J Basic Clin Physiol Pharmacol, 32, 297-304.
Alfian, R., Nita, Y. & Athiyah, U. 2025b. Evaluation of Pharmacist-Based Services for Type 2 Diabetes Mellitus in the Indonesian Community Health Centers. Journal of Public Health and Pharmacy, 5, 1-10.
Almeman, A. 2024. The digital transformation in pharmacy: embracing online platforms and the cosmeceutical paradigm shift. J Health Popul Nutr, 43, 60.
Alsaidan, A. A., Alotaibi, S. F., Thirunavukkarasu, A., Bf, A. L., Alharbi, R. H., Arnous, M. M., Alsaidan, O. A., Alduraywish, A. S. & Alwushayh, Y. A. 2023. Medication Adherence and Its Associated Factors among Patients with Type 2 Diabetes Mellitus Attending Primary Health Centers of Eastern Province, Saudi Arabia. Medicina (Kaunas), 59.
Alsairafi, Z., Waheedi, M. & Alsaleh, F. 2019. The perspectives of patients and physicians on the role of pharmacists in improving medication adherence in type 2 diabetes: a qualitative study. Patient Prefer Adherence, 13, 1527-1543.
Antar, S. A., Ashour, N. A., Sharaky, M., Khattab, M., Ashour, N. A., Zaid, R. T., Roh, E. J., Elkamhawy, A. & Al-Karmalawy, A. A. 2023. Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments. Biomed Pharmacother, 168, 115734.
Bakhsh, H. T. 2025. Impact of Pharmacist Interventions on Health Outcomes of Patients with Type 2 Diabetes Mellitus in the Middle East: A Systematic Review. Integr Pharm Res Pract, 14, 85-98.
Boonpattharatthiti, K., Songkla, P. N., Chantara, J., Koomsri, C., Krass, I., Chaiyakunapruk, N. & Dhippayom, T. 2024. Prevalence of adherence to oral antidiabetic drugs in patients with type 2 diabetes: A systematic review and meta-analysis. J Diabetes Investig.
Ghanbari-Jahromi, M., Kharazmi, E., Bastani, P., Shams, M., Marzaleh, M. A. & Amin Bahrami, M. 2024. Factors disrupting the continuity of care for patients with chronic disease during the pandemics: A systematic review. Health Sci Rep, 7, e1881.
Habte, B. M., Kebede, T., Fenta, T. G. & Boon, H. 2017. Barriers and facilitators to adherence to anti-diabetic medications: Ethiopian patients’ perspectives. Afr J Prm Health Care Fam Med., 9.
Hashimoto, K., Urata, K., Yoshida, A., Horiuchi, R., Yamaaki, N., Yagi, K. & Arai, K. 2019. The relationship between patients’ perception of type 2 diabetes and medication adherence: a cross-sectional study in Japan. Journal of Pharmaceutical Health Care and Sciences, 5.
Hidayat, B., Ramadani, R. V., Rudijanto, A., Soewondo, P., Suastika, K. & Siu Ng, J. Y. 2022. Direct Medical Cost of Type 2 Diabetes Mellitus and Its Associated Complications in Indonesia. Value Health Reg Issues, 28, 82-89.
Hossain, M. J., Al-Mamun, M. & Islam, M. R. 2024. Diabetes mellitus, the fastest growing global public health concern: Early detection should be focused. Health Sci Rep, 7, e2004.
IDF 2021. IDF Diabetes Atlas 10th edition, International Diabetes Federation.
Jaam, M., Mohamed Ibrahim, M. I., Kheir, N., Hadi, M. A., Diab, M. I. & Awaisu, A. 2018. Assessing prevalence of and barriers to medication adherence in patients with uncontrolled diabetes attending primary healthcare clinics in Qatar. Prim Care Diabetes, 12, 116-125.
Kardas, P., Mogilevkina, I., Aksoy, N., Agh, T., Garuoliene, K., Lomnytska, M., Istomina, N., Urbanavice, R., Wettermark, B. & Khanyk, N. 2025. Barriers to healthcare access and continuity of care among Ukrainian war refugees in Europe: findings from the RefuHealthAccess study. Front Public Health, 13, 1516161.
Kassavou, A. & Sutton, S. 2017. Reasons for non-adherence to cardiometabolic medications, and acceptability of an interactive voice response intervention in patients with hypertension and type 2 diabetes in primary care: a qualitative study. BMJ Open, 7, e015597.
Kemenkes 2023. Survey Kesehatan Indonesia (SKI) Dalam Angka, Jakarta, Indonesia, Kementrian Kesehatan Indonesia.
Khunti, N., Khunti, N. & Khunti, K. 2019. Adherence to type 2 diabetes management. British Journal of Diabetes, 19, 99-104.
Kutluay, N. B., Bektay, M. Y., Sumbul-Sekerci, B., Sekerci, A. & Izzettin, F. V. 2025. Impact of clinical pharmacist integration on diabetes management: a prospective cohort. BMC Health Serv Res, 25, 107.
Kvarnstrom, K., Westerholm, A., Airaksinen, M. & Liira, H. 2021. Factors Contributing to Medication Adherence in Patients with a Chronic Condition: A Scoping Review of Qualitative Research. Pharmaceutics, 13.
Padhi, S., Nayak, A. K. & Behera, A. 2020. Type II diabetes mellitus: a review on recent drug based therapeutics. Biomed Pharmacother, 131, 110708.
Pertiwi, M. V., Alfian, R., Nita, Y. & Athiyah, U. 2022. Medication adherence of diabetes mellitus patients in Indonesia: A systematic review. Pharmacy Education, 188-193.
Pourhabibi, N., Sadeghi, R., Mohebbi, B., Shakibazadeh, E., Sanjari, M., Tol, A. & Yaseri, M. 2022. Factors affecting nonadherence to treatment among type 2 diabetic patients with limited health literacy. Journal of Education and Health Promotion, 11.
Presley, B., Groot, W., Widjanarko, D. & Pavlova, M. 2021. Preferences for pharmacist services to enhance medication management among people with diabetes in Indonesia: A discrete choice experiment. Patient Educ Couns, 104, 1745-1755.
Rezaei, M., Valiee, S., Tahan, M., Ebtekar, F. & Ghanei Gheshlagh, R. 2019. Barriers of medication adherence in patients with type-2 diabetes: a pilot qualitative study. Diabetes Metab Syndr Obes, 12, 589-599.
Schwarz, T., Schmidt, A. E., Bobek, J. & Ladurner, J. 2022. Barriers to accessing health care for people with chronic conditions: a qualitative interview study. BMC Health Serv Res, 22, 1037.
Thangiah, G., Johar, H., Ismail, R., Reininghaus, U., Bärnighausen, T., Thurairajasingam, S., Reidpath, D. & Su, T. T. 2022. Diabetes Treatment and Mental Illness: A Call for an Integrated Health Care System in Underserved Semi-Rural Malaysia. International Journal of Environmental Research and Public Health, 19.
Uddin, S., Sanchez Machado, M., Alshahrouri, B., Echeverri, J. I., Rico, M. C., Rao, A. D., Ruchalski, C. & Barrero, C. A. 2025. Empowering Pharmacists in Type 2 Diabetes Care: Opportunities for Prevention, Counseling, and Therapeutic Optimization. J Clin Med, 14.
Untari, I., Utami, S., Hafiduddin, M., Yakob, A., Kusumawati, Y., Alfiyani, L., Rahayu, U. B., Hamranani, S. S. T. & Umam, D. N. 2024. Relationship Between Medication Adherence and Blood Sugar Levels Among Diabetes Mellitus Outpatients. Media Kesehatan Masyarakat Indonesia, 20, 39-45.
WHO 2003. Adherence To Long-Term Therapies : Evidence For Action, Geneva. , World Health Organization.
Wibowo, Y., Parsons, R., Sunderland, B. & Hughes, J. 2015. An evaluation of community pharmacy-based services for type 2 diabetes in an Indonesian setting: patient survey. PeerJ, 3, e1449.
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